摘要
目的研讨脑梗塞患者使用阿托伐他汀与氯吡格雷两药治疗的临床价值。方法选择2017年6月至2018年6月我院收治的100例脑梗塞患者参与实验观察,并将患者随机分为两组,Ⅰ组(n=50)接受常规基础治疗,Ⅰ组(n=50)在Ⅰ组基础用药下接受阿托伐他汀与氯吡格雷口服,分析评估两组治疗对临床药效、患者神经功能状况等指标的影响。结果对比Ⅰ组,Ⅰ组患者在临床药效方面有显著提升,有统计学意义(P<0.05)。治疗前,两组在神经功能缺损评分、CRP水平上的对比,无统计学意义(P> 0.05);治疗后,Ⅰ组在神经功能缺损评分与CRP水平上较Ⅰ组均显著改善,有统计学意义(P<0.05)。结论对脑梗塞患者使用阿托伐他汀与氯吡格雷两药治疗有显著的药效,且能够缓解神经缺损症状,加速清除炎性因子,值得推荐。
Objective Clinical value of atorvastatin and clopidogrel in the treatment of cerebral infarctionpatients by two drugs. Methods From June 2017 to June 2018, 100 patients with cerebral infarction in our hospital wereselected to participate in the experimental observation. The patients were randomly divided into two groups. GroupⅠ (n=50) received routine basic treatment, and group Ⅰ (n=50) received oral atorvastatin and clopidogrel on the basisof group Ⅰ. The effects of two groups of treatment on clinical efficacy and neurological function were analyzed andevaluated. Results Compared with group Ⅰ, group Ⅰ patients had a significant improvement in clinical efficacy (P<0.05).Before treatment, there was no significant difference in the scores of neurological deficits and CRP between the twogroups (P>0.05). After treatment, the scores of neurological deficits and CRP in group Ⅰ were significantly improvedcompared with group Ⅰ. Academic significance (P<0.05). Conclusion Atorvastatin and clopidogrel have significantefficacy in the treatment of cerebral infarction patients, and can alleviate the symptoms of nerve defects, accelerate theremoval of inflammatory factors, worthy of recommendation.
作者
金玉兰
JIN Yu-lan(Tonghua People's Hospital,Tonghua,Jilin 134100)
出处
《智慧健康》
2018年第32期144-145,148,共3页
Smart Healthcare
关键词
脑梗塞
阿托伐他汀
氯吡格雷
临床价值
Cerebral infarction
Atorvastatin
Clopidogrel
Clinical value
