摘要
目的探究分析泮托拉唑和奥美拉唑对胃溃疡的治疗效果。方法选取石嘴山市第一人民医院自2014年1月~2016年6月收治的胃溃疡治疗患者共100例作为研究对象,随机分为对照组和实验组,每组50例。对照组予以奥美拉唑治疗,实验组组予以泮托拉唑治疗。服用药物1个疗程后,比较2组临床疗效、治疗费用、幽门螺旋杆菌根除率以及胃溃疡复发率。结果实验组的总有效率94%,显著高于对照组的72%,差异有统计学意义（P〈0.05）。经过对应的治疗后,实验组50例患者中,幽门螺旋杆菌根除率为72.0%,胃溃疡复发率为12.0%。对照组50例中,幽门螺旋杆菌根除率为52.0%,胃溃疡复发率为36.0%。由此可得,实验组患者的幽门螺旋杆菌根除率显著高于对照组。对照组的治疗费用为（499.78±74.81）元,实验组治疗费用为（413.26±56.39）元。可得,对照组患者的治疗费用以及胃溃疡复发率显著高于实验组患者,差异具有统计学意义（P〈0.05）。结论泮托拉唑治疗胃溃疡的效果比奥美拉唑要好得多,治疗有效率较高,是治疗胃溃疡的首选药,治疗后胃溃疡复发率较低,治疗费用较低且根除率高,具有进一步在临床推广和应用的意义。
Objective To investigate and analyze the effect of pantoprazole and omeprazole in the treatment of gastric ulcer. Methods a total of100 patients with gastric ulcer treated in Shizuishan First People＇s Hospital from January 2014 to June 2016 were selected and randomly divided into the control group and the experimental group,with 50 patients in each group. The control group was treated with omeprazole,and the experimental group was treated with pantoprazole. After taking one course of treatment,the clinical efficacy,treatment cost,eradication rate of Helicobacter pylori and recurrence rate of gastric ulcer were compared between the 2 groups. Results The total effective rate of the experimental group was 94%,which was significantly higher than that of the control group（ 72%）,and the difference was statistically significant（ P〈 0. 05）. After the corresponding treatment,the experimental group of 50 cases,Helicobacter pylori eradication rate was 72%,the recurrence rate of gastric ulcer was 12%. In the control group of 50 cases,the eradication rate of Helicobacter pylori was 52%,and the recurrence rate of gastric ulcer was 36%. As a result,the eradication rate of H. pylori in the experimental group was significantly higher than that in the control group. The cost of treatment in the control group was（ 499. 78 ±74. 81） yuan,and the treatment cost of the experimental group was（ 413. 26 ± 56. 39） yuan. The treatment cost and gastric ulcer recurrence rate in the control group were significantly higher than those in the experimental group,with statistical difference（ P〈 0. 05）. Conclusion Pantoprazole in the treatment of gastric ulcer is much better than omeprazole,high treatment efficiency,is the preferred drug for the treatment of gastric ulcer,after the treatment of gastric ulcer recurrence rate is low,the cost of treatment is low and high eradication rate,with the further promotion and application in clinic significance.
出处
《中国生化药物杂志》
CAS
2017年第7期239-240,243,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
胃溃疡
泮托拉唑
奥美拉唑
gastric ulcer
pantoprazole
omeprazole
作者简介
汤纳，通信作者，男，本科，主治医师，研究方向：消化系统疾病，E—mail：hongsongx1@163．com
