摘要
目的:观察清热利湿补肾活血汤治疗湿热痹阻型强直性脊柱炎患者的临床疗效。方法:选取76例湿热痹阻型强直性脊柱炎患者随机分为两组各38例,治疗组给予清热利湿补肾活血汤治疗,对照组予西药治疗,比较两组患者临床疗效、治疗前后实验室指标、临床指标改善及不良反应发生情况。结果:治疗组临床总有效率为92.11%,显著高于对照组的71.05%,ESR和CRP值低于对照组,治疗后晨僵时间、VAS评分、Schober试验及指地距改善优于对照组患者,不良反应发生率(5.26%)较对照组患者(26.32%)显著降低,差异具有统计学意义(P<0.05)。结论 :清热利湿补肾活血汤治疗湿热痹阻型强直性脊柱炎可显著提高临床疗效,改善患者的临床症状,降低不良反应发生率。
Objective： To observe the clinical effects of qingre lishi bushen huoxue decoction on ankylosing spondylitis of dampness-heat impeding . Methods： 76 cases of selected patients with ankylosing spondylitis of dampness-heat impeding were randomly divided into treatment group and control group, 38 cases in each group. The treatment group was treated with qingre lishi bushen huoxue decoction, while the control group was trea- ted with western medicine. The clinical effects, the laboratory check indexes before and after treatment, the clini- cal improvement indexes, and the incidence of adverse reactions of patients were compared between two groups. Results： The clinical total effective rate of treatment group was 92. 11%, which was significantly higher than 71.05 % total effective rate of control group. ESR and CRP values of patients in treatment group were lower than those in control group. After treatment, morning stiffness time, VAS scores, Schober experiment and improve- ment of pointing ground of patients were in treatment better than those in control group. The incidence of adverse reactions in treatment group was 5.26%, which was obviously lower than 26. 32% in control group. The difference between two groups was statistically significant （ P 〈 0.05 ）. Conclusion ： Qingre lishi bushen huoxue decoction for ankylosing spondylitis of dampness-heat impeding can obviously enhance the clinical effect, improve the clinical symptoms of patients and reduce the incidence of adverse reactions.
出处
《山西中医》
2016年第4期10-12,共3页
Shanxi Journal of Traditional Chinese Medicine
关键词
强直性脊柱炎
湿热痹阻
清热利湿补肾活血汤
中医药疗法
ankylosing spondylitis, dampness -heat impeding, qingre lishi bushen huoxue decoction, therapy of TCM
作者简介
作者简介：谢春亮（1977-），男，主治中医师，广东省广州市中西医结合医院（广州510800）。
