摘要
目的:探讨类风湿性关节炎中医证型与抗环瓜氨酸肽抗体(抗CCP抗体)之间的关系。方法:选取正常对照组42例,类风湿性关节炎患者183例(湿热痹阻型45例,痰瘀痹阻型28例,寒湿痹阻型40例,风湿痹阻型32例,肝肾不足型21例,气血两虚型17例),检测两组人群的抗CCP抗体。结果:类风湿性关节炎患者组抗CCP抗体阳性率及检测值明显高于正常对照组,在不同证型的类风湿性关节炎患者中,以湿热痹阻型患者抗CCP抗体的检测值最高。结论:抗CCP抗体可以作为中医辨证分型的一个参考指标。
Objective： To investigate the relationship between traditional Chinese medicine（ TCM） syndrome types and anti- cyclic citrullinated peptide（ CCP） antibody in patients with rheumatoid arthritis. Methods： This study included 42 normal controls and 183 patients with rheumatoid arthritis. The patients with rheumatoid arthritis consisted of 45 cases of damp- heat obstruction,28 cases of phlegm- stasis obstruction,40 cases of cold- damp obstruction,32 cases of wind- damp obstruction,21 cases of deficiency of liver and kidney,and 17 cases of qi- blood deficiency. The level of anti- CCP antibody was determined for the two groups. Results： The rheumatoid arthritis group had significantly higher positive anti- CCP antibody rate and anti- CCP antibody level than the normal control group. Among the patients with rheumatoid arthritis,those with damp- heat obstruction had the highest anti- CCP antibody level. Conclusion： Anti- CCP antibody can be used as a reference index for TCM syndrome differentiation in patients with rheumatoid arthritis.
出处
《湖南中医杂志》
2016年第3期1-3,共3页
Hunan Journal of Traditional Chinese Medicine
关键词
类风湿关节炎
中医证型
抗环瓜氨酸肽抗体
相关性
rheumatoid arthritis
traditional Chinese medicine syndrome type
anti-cyclic citrullinated peptide antibody
relationship
作者简介
李巧，女，2013级硕士研究生，研究方向：风湿免疫性疾病的诊疗
通讯作者：范伏元，男，主任医师，硕士研究生导师，研究方向：呼吸系统及风湿免疫性疾病的诊疗
