摘要
目的分析136例维吾尔族类风湿关节炎(RA)患者的中医证型及实验室指标。方法选取2016年1月—2017年6月在新疆维吾尔自治区中医院风湿科住院的136例维吾尔族类风湿关节炎患者,记录其临床特点、中医证型及实验室指标,并进行统计分析。结果其中痰瘀痹阻证(30.9%)居多,其次依次为湿热痹阻证(25.7%)、寒湿痹阻证(22.1%)、肝肾亏虚证(21.3%)。肝肾亏虚证碱性磷酸酶及球蛋白水平均高于寒湿痹阻证,二者比较差异有统计学意义(p <0.05);湿热痹阻证D-二聚体水平高于肝肾亏虚证,二者比较差异有统计学意义(p<0.05);湿热痹阻证血沉水平及DAs28评分均高于寒湿痹阻证,二者比较差异有统计学意义(p <0.05)。结论维吾尔族类风湿关节炎患者中,临床多见痰瘀痹阻证;肝肾亏虚证类风湿关节炎患者更易出现骨代谢紊乱,而湿热痹阻证类风湿关节炎患者疾病活动度高,病情较重。
Objective To Analysis of TCM syndromes and laboratory indicators of 136 Uyghur patients with rheumatoid arthritis(RA).Methods Choosing 136 cases hospitalized Uyghur RA patients from January 2016 to June 2017 in Xinjiang Uyghur autonomous region TCM Hospital,the clinical features,TCM Syndromes and laboratory indicators were recorded and statistically analyzed.Results The majority of the syndromes were phlegm stasis syndrome which accounted for 30.9%,next came moist heat arthralgia spasm syndrome,cold-dampness stasis syndrome and athenia of liver and kidney syndrome which accounted for 25.7%,22.1%and 21.3%respectively.The serum alkaline phosphatase and globulin levels in athenia of liver and kidney syndrome were higher than colddampness stasis syndrome,the differences of two pattern had statistically significant(P<0.05).The D-dimer levels in moist heat arthralgia spasm syndrome were higher than athenia of liver and kidney syndrome,the differences of two syndrome had statistically significant(P<0.05).The ESR levels and DAS28 scales in moist heat arthralgia spasm syndrome were higher than cold-dampness stasis syndrome,the differences of two syndrome had statistically significant(P<0.05).Conclusion The sputum-silting impeding pattern was common of Uyghur RA patients in the clinical.RA patients of athenia of liver and kidney syndrome were more likely to appear bone metabolic disorders.RA patients of moist heat arthralgia spasm syndrome show high activity of the disease and severe disease condition.
作者
陈慕芝
吕蕾
照日格图
CHEN Muzhi;LYU Lei;ZHAORI Getu(Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University,Urumqi 830000,China)
出处
《吉林中医药》
2019年第4期464-467,共4页
Jilin Journal of Chinese Medicine
基金
新疆维吾尔自治区自然科学基金项目(2016D01C149)
关键词
类风湿关节炎
中医证候
维吾尔族
痰瘀痹阻
湿热痹阻
rheumatoid arthritis
TCM syndrome
Uyghur
syndrome of intermin-gled phlegm and blood stasis
damp-heat syndrome
作者简介
陈慕芝(1982-),女,硕士,副主任医师,主要从事中西医结合风湿病研究;通信作者:照日格图,男,电话-13579429967,电子信箱-3419353450@qq.com.
