摘要
目的:用循证医学的方法评价清胰汤治疗急性胰腺炎的临床疗效。方法:检索2014年9月之前发表的有关清胰汤治疗急性胰腺炎疗效的随机对照临床试验。按照纳入标准,有12项符合要求的临床试验纳入本研究,由2名评价者对入选研究中有关实验设计、研究对象的特征、研究结果等内容进行摘录,用Rev Man5.3软件进行Meta分析。结果:本Meta分析共纳入12个试验(838例急性胰腺炎患者),其中9个试验总有效率的Meta分析结果显示清胰汤联合西医常规治疗组的腹痛缓解时间(WMD=-2.22,95%CI:-2.85^-1.59,P<0.00001)明显优于对照组,8个试验总有效率的Meta分析结果显示血淀粉酶恢复时间(WMD=-1.82,95%CI:-2.58^-1.06,P<0.00001)明显优于对照组,差异有统计学意义。结论:本Meta分析提示清胰汤联合西药治疗急性胰腺炎有明显疗效。
Objective： To evaluate clinical efficacy of the Qing Yi decoction on acute pancreatitis by the method of evidence-based medicine. Methods： The randomized controlled clinical trials of treating acute pancreatitis with the Qing Yi decoction published before September 2014 were retrieved. According to the inclusion criteria, 12 items meeting the requirement were included in this study. The design of experiment, the character of research object and the results of research in this study were excerpted by two evaluators, and analyzed by Rev Man 5.3 software. Results： 12 trials were included in this Meta-analysis（838 cases of acute pancreatitis）; 9 trials＇ total efficiency of the Meta-analysis showed that the time for allewiating abdominal pain with the Qing Yi decoction plus conventional western、（WMD =-2.22, 95%CI：-2.85 --1.59, P〈0.00001） was obviously better than that in the control group, and 8 trials＇ total efficiency of the Meta-analysis showed that blood amylase recovery time（ WMD=-1.82, 95%CI：-2.58--1.06, P〈0.00001） was obviously better than that in the control group, with statistical significant difference. Conclusion： The Meta-analysis suggested that the Qing Yi decoction plus western medicine could gain obvious efficacy on acute pancreatitis.
出处
《中医临床研究》
2015年第34期9-13,共5页
Clinical Journal Of Chinese Medicine
关键词
急性胰腺炎
腹痛
清胰汤
随机
临床试验
META分析
Acute pancreatitis
Abdominal pain
The Qing Yi decoction
Random
Clinical trials
A Meta-analysis
作者简介
胡芳齐，女，在读硕士研究生，研究方向为消化系统疾病的中西医结合诊疗。
郑亿濠，男，在读硕士研究生，研究方向为消化系统疾病的中西医结合诊疗。
