摘要
胃癌是我国最常见的恶性肿瘤之一,其发病率和病死率在恶性肿瘤中分别位于第二位和第三位。胃癌是慢性炎症状态(尤其是幽门螺杆菌感染)所触发的慢性萎缩性胃炎、肠上皮化生、异型增生等多步级联效应的最后一步。胃癌前病变的防治重在控制或去除已知危险因素,包括以新鲜果蔬为主的饮食干预来减轻氧化损伤,根除幽门螺杆菌,抑制黏膜炎症反应。对于已经发现的癌前疾病,应该加强治疗与内镜监测。寻找有效化学预防措施阻断癌前病变的发展已成为胃癌预防的迫切需要。
Gastric cancer is one of the most common cancers m ~nm~. l~ ,,, ~ third in the malignancy. Gastric cancer is the final step in a multi-stage cascade triggered by long standing inflammatory conditions （particularly Helicobacter pylori infection）, resulting in atrophic gastritis, intestinal metaplasia and dysplasia. The prevention and clinical management of gastric precancerous conditions should put the stress on controlling or getting rid of risk factors, such as alleviating oxidative stress with fresh vegetables and fruits, Hdicobacter pylori eradication, and inhibiting inflammation of gastric mucosa. For existing precancerous diseases, prompt treatment and endoscopic monitoring are necessary. It is of urgent request to search out effective ways of chemoprevention to repress precancerous lesions.
出处
《医学与哲学（B）》
2015年第11期16-18,共3页
Medicine & Philosophy(B)
关键词
胃癌
癌前疾病
癌前病变
预防
gastric carcinoma, precancerous condition, precancerous lesion, prevention
作者简介
姚树坤（1957-），男，河北衡水人，博士，教授，主任医师，研究方向：消化道肿瘤，功能性胃肠病。
