摘要
目的通过医院感染现患率调查中抗菌药物使用的相关数据,了解和掌握本院抗菌药物的使用的基本情况,评价抗菌药物合理使用干预成效。方法分别对青海大学附属医院抗菌药物合理应用专项整治前(2010年)后(2012、2014年)3年的感染现患率调查中当日在院患者的抗菌药物使用情况的相关数据进行资料统计分析,观察比较抗菌药物使用情况、预防性用药占比、患者标本微生物送检情况、出院患者抗菌药物使用率及用药频度值。结果本院全院调查当日抗菌药物使用率逐年下降[41.11%(645/1569)、25.88%(434/1677)、15.97%(315/1972),x^2=278.69,P〈0.01]、联合使用抗菌药物比例逐年下降[14.73%(95/645)、6.91%(30/434)、5.71%(18/315),x^2=21.59,P〈0.01]、预防性抗菌药物使用比例逐年下降[38.29%(247/645)、29.03%(126/434)、26.98%(85/315),x^2=14.22,P〈0.01],使用抗菌药物治疗患者微生物标本送检率逐年提高[10.55%(42/398)、40.26%(124/308)、47.39%(109/230),x^2=126.37,P〈0.01]。出院患者抗菌药物使用率及用药频度值逐年下降[72.43%(25974/35861)、56.11%(25253/45006)、42.67%(26080/61120),x^2=71.37:48.64、43.27、29.00,x^2=8.28;均P〈0.01]。结论自抗菌药物合理应用专项整治开始后,本院多部门联动开展抗菌药物合理使用指导活动的干预效果明显,抗菌药物使用逐步趋于合理。
Objective To evaluate the basic situation of antibiotics using and assess the effect of rational antibiotics control intervention through the relevant date of antibiotics using by nosocomial ince survey before (2010) annfection (NI) pointprevalence survey. Methods The using situation of antibiotics on the index day of NI prevalence point-prevaled after special rectification activities of antibacterial drug utilization (2012 and 2014) were analyzed. The rate of antibacterial drug and preventive antibiotics, the rate of microorganism specimen sub- mission, the rate and frequency of antibiotic in discharged patients using were analyzed. Results The survey showed that the utilization rate of antibacterial drug on the day was decreased year by year [ 2010:41.11% (645/ 1 569), 2012: 25.88% (434/1 677), 2014: 15.97% (315/1 972) ] (x^2= 278.69, P 〈0. 01). The rate of multiple antibiotics using was decreased year by year [2010: 14. 73% (95/645), 2012: 6.91% (30/434) , 2014:5.71 ( 18/315 ) ] (x^2 = 21.59, P 〈 0. 01 ). The rate of preventive antibiotics using was decreased year by years [2010: 38.29% (247/645), 2012: 29.03% (126/434), 2014: 26. 98% (85/315)] (x^2=14.22, P〈 0. 01 ). The rate of microorganism specimen submission was increased year by year [2010: 10. 55% (42/398), 2012: 40. 26% (124/308) , 2014: 47.39% (109/230) ] (x^2 = 126.37, P 〈 0. 01 ). The rate of antibiotic using in discharged patients was decreased year by year [ 2010: 72.43% (25 974/35 861 ), 2012: 56. 11% ( 25 253/45 006), 2014: 42. 67% (26 080/61 120) ] (x^2 = 71.37, P 〈 0. 01 ), so did the frequency of drug use (2010: 48.64, 2012: 43.27, 2014: 2.9) (x^2 = 8.28, P 〈 0. 01 ). Conclusion In recent years, the use of antibiotics tends to be reasonable gradually after special rectification activities of antibacterial drug utilization in Qinghai University Affiliated Hospital.
出处
《中国医药》
2015年第12期1845-1848,共4页
China Medicine
关键词
医院感染
现患率调查
抗菌药物
Nosocomial infection
Prevalence survey
Antibiotics
作者简介
通信作者:张永栋,Email:610194826@qq.com