摘要
目的:本研究基于数据挖掘分析的方法,对《清宫医案集成》中止咳类方药进行初步归纳并总结临床经验论治规律,并对其咳嗽的治疗经验进行探讨。方法:筛选清宫医案113首止咳方剂,统计其中各药的使用频率,利用数据挖掘分析不同药味在治疗咳嗽中的使用规律。结果:常用止咳中药出现频率前5位:甘草、茯苓、桔梗、半夏、陈皮。止咳中药按类型统计,使用频率前5位:理气药、清热化痰、补气药、止咳平喘药、温化寒痰药。关联性分析结果得出:陈皮与其他多种药物关联性最强,其次是甘草、茯苓、半夏等,而陈皮+桔梗、桔梗+茯苓、茯苓+半夏药对关联性明显强于其他两两药物之间的关系。置信度和支持度分析:陈皮+枳壳+茯苓、陈皮+黄芩+茯苓、陈皮+半夏+茯苓、陈皮+半夏+甘草+茯苓的置信度为100%。结论:咳嗽的病机在《清宫医案集成》中以"肺气不宣肺失宣肃"为主,组方多用理气、行气、化痰之法,佐以疏风清热、活血化瘀等法。
Objective： This study preliminary summarized the anti-cough formulas and medicines and clinical experience in Medical Records Integration of Palace in Qing Dynasty, and discussed the experience in the treatment of cough based on data mining. Methods： 113 anti-cough formulas in medical records of palace in Qing Dynasty were screened, and the law of drug use in cough treatment was analyzed with data mining. Results： Drugs with using frequency in the top five pick were liquorice root, indian buead, platycodon root, pinellia tuber and dried tangerine peel. Types of medicines with using frequency in the top five pick were qi regulated drugs, heat-clearing and phlegm-transforming drugs, qi-tonifying drugs, cough-suppressing and panting- calming drugs, and warmly resolving cold-phlegm drugs. The result of correlation analysis showed that the relationship between dried tangerine peel correlated other drugs was the strongest, followed by liquorice root, indian buead and pinellia tuber. The relationships of herb pairs such as dried tangerine peel and platycodon root, platycodon root and indian buead, indian buead and pinellia tuber were stronger than that of other two drugs. The results of analysis on support and confidence showed that the confidence of dried tangerine peel＋fruit of trifoliate orange＋indian buead, dried tangerine peel＋baical skullcap root＋indian buead, dried tangerine peel＋pinellia tuber＋indian buead and dried tangerine peel＋pinellia tuber＋liquorice root＋indian buead was 100%. Conclusion： The pathogenesis of cough in Medical Records Integration of Palace in Qing Dynasty was that the functions of governing diffusion and governing purification and descending of lung were disorder, so the treatment formulas gave priority to qi regulated, promoting the circulation of qi and phlegm-resolving, and assisted with treatment of dispelling wind to clear heat and promoting blood circulation for removing blood stasis.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2015年第1期270-273,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
数据挖掘
关联性
止咳药
组方原则
清宫医案集成
Data mining
Association
Anti-cough medicine
Principles of formulating prescription
Medical Records Integration of Palace in Qing Dynasty
作者简介
通讯作者：徐凤芹，海淀区西苑西苑操场1号中国中医科学院西苑医院，邮编：100091，电话：010—62835397E—mail：rebeaca1988@sina．com
