摘要
目的:采用Meta分析法评价心理干预对中国宫颈癌放化疗患者负性情绪及生活质量的影响。方法:检索2009～2018年中国知网、万方数据库、中国生物医学文献数据库、Web of Science、Cochrane Library和PubMed等数据库,收集相关文献,使用Review Manager 5.3软件分析心理干预前后干预组与对照组焦虑自评量表(self-rating anxiety scale,SAS)、抑郁自评量表(self-rating depression scale,SDS)、癌症患者生命质量测定量表(quality of life scale of european organization for research and treatment of cancer,EORTC QLQ-C30)以及症状自评量表(symptom checklist 90,SCL-90)的得分差异。结果:最终纳入16篇随机对照研究文献,其中干预组762例,对照组756例。Meta分析结果显示,心理干预后干预组SAS、SDS、SCL-90中抑郁、焦虑、躯体化与人际关系敏感得分明显低于对照组,差异有显著统计学意义(P<0.01),干预组EORTC QLQ-C30中躯体功能、角色功能、认知功能、情绪功能与社会功能得分明显高于对照组,差异有统计学意义(P<0.05)。结论:现有文献资料表明,心理干预可有效改善宫颈癌放化疗患者负性情绪,提高其生活质量。
Objective:To investigate the effect of psychological intervention on negative emotion and quality of life in patients with cervical cancer accepted chemoradiotherapy by Meta analysis.Methods:By searching CNKI,Wanfang database,CBM database,Web of Science data-base,Cochrane Library and PubMed database from 2009 to 2018 to collected relevant documents,and Review Manager 5.3was used to calculate the difference between negative emotion and quality of life before and after intervention.The level of negative emotion and quality of life was evaluated by the self-rating anxiety scale (SAS),self-rating depression scale (SDS),quality of life scale of european organization for research and treatment of cancer (EORTC QLQ-C30) and symptom checklist 90 (SCL-90).Results:Sixteen randomized controlled trials were included,762patients in the intervention group and 756patients in the control group.The results showed that the scores of depression,anxiety,somatization and interpersonal sensitivity of SCL-90,SAS and SDS after psychological intervention in the intervention group were significantly lower than those in the control group(P<0.01).The scores of physical function,role function,cognitive function,emotional function and social function of EORTC QLQ-C30in the intervention group were significantly higher than those in the control group(P<0.05).Conclusion:The existing literature shows that psychological intervention can effectively reduce the negative emotions of patients with cervical cancer undergoing radiotherapy and chemotherapy,improve their quality of life.
作者
黄闻
张小茹
张翀旎
HUANG Wen;ZHANG Xiaoru;ZHANG Chongni(The First Affiliated Hospital of Nanchang University Department of Psychosomatic Medicine,Nanchang 330006,China;The First Affiliated Hospital of Nanchang University Department of Gynecology & Obstetrics,Nanchang 330006,China)
出处
《西北国防医学杂志》
CAS
2018年第11期711-716,共6页
Medical Journal of National Defending Forces in Northwest China
基金
南昌大学研究生教学案例库建设项目(9202-0210210802)
关键词
宫颈癌
心理干预
抑郁
焦虑
生活质量
META分析
cervical cancer
psychological intervention
depression
anxiety
quality of life
Meta analysis
作者简介
黄闻(1993-),女,在读硕士,E-mail:huangw512@126.com;通讯作者:张翀旎,E-mail:zhangchni@126.com
