摘要
目的探讨网络化持续康复护理支持对宫颈癌术后化疗患者遵医行为及细胞因子的影响。方法选取2016年7月至2019年7月间营口市中心医院收治的78例宫颈癌术后化疗患者,采用随机数表法分为研究组和对照组,每组39例。对照组患者采用常规护理,研究组患者在对照组基础上采用网络化持续康复护理支持,比较两组患者遵医行为、血清脑源性神经营养因子(BDNF)、5-羟色胺(5-HT)和负性情绪(焦虑和抑郁评分)。结果研究组患者遵医总依从率为97.4%,高于对照组的76.9%,差异有统计学意义(P<0.05)。干预前,两组患者BDNF和5-HT水平比较,差异无统计学意义(P>0.05)。干预后,两组患者BDNF和5-HT水平均提高,且研究组均高于对照组,差异均有统计学意义(P<0.05)。干预前,两组患者焦虑和抑郁评分比较,差异无统计学意义(P>0.05)。干预后,两组患者焦虑和抑郁评分均降低,且研究组均低于对照组,差异均有统计学意义(P<0.05)。结论网络化持续康复护理支持应用于宫颈癌术后化疗患者,可提高患者遵医依从性,调节细胞因子BDNF和5-HT水平,改善负性情绪。
Objective To explore the effects of network-based continuous rehabilitation nursing support on medical compliance behavior and cytokines in patients receiving postoperative chemotherapy for cervical cancer.Methods Seventy-eight patients receiving postoperative chemotherapy for cervical cancer who admitted to Yingkou Central Hospital from July 2016 to July 2019 were enrolled in the study.They were divided into a study group and a control group using the random number table method with 39 patients in each group.The study group received network-based continuous rehabilitation nursing support besides routine care and the control group only received routine nursing care.Medical compliance behavior,cytokine levels including brain derived neurotrophic factor(BDNF)and 5-hydroxytryptamine(5-HT),and negative emotions(scores of anxiety and depression)were compared between the two groups.Results The overall medical compliance rate was 97.4%in the study group which was higher than 76.9%of the control group(P<0.05).There was no significant difference in the levels of BDNF and 5-HT between the two groups before the intervention(P>0.05).After the intervention,the levels of BDNF and 5-HT increased in both groups with the study group higher than the control group(all P<0.05).Before the intervention,there was no significant difference in the scores of self-rating depression scale(SDS)and self-rating anxiety scale(SAS).After the intervention,scores of SAS and SDS decreased in both groups with the study group lower than the control group(all P<0.05).Conclusion Network-based continuous rehabilitation nursing support can significantly improve medical compliance,regulate cytokine BDNF,5-HT levels,and improve negative emotions in patients receiving postoperative chemotherapy for cervical cancer.
作者
陈颖
曲萃辉
张雪
CHEN Ying;QU Cui-hui;ZHANG Xue(Department of Gynecology and Obstetrics,Yingkou Central Hospital,Yingkou 115003,China)
出处
《中国肿瘤临床与康复》
2020年第2期225-228,共4页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
宫颈肿瘤
网络化
康复护理
遵医行为
细胞因子
负性情绪
Cervical neoplasms
Network
Rehabilitation nursing
Medical compliance behavior
Cytokines
Negative emotions
作者简介
陈颖,女,副主任护师,主要从事妇产科护理专业。
