摘要
目的研究番木瓜籽中苄基硫代葡萄糖苷(BG)对小鼠免疫活性的影响。方法以制备得到的BG粗品为研究对象,研究其对小鼠体液免疫、非特异性免疫、脏器指数以及脏器组织形态的影响。结果 BG粗品能显著提高小鼠的胸腺指数、促进血清溶血素的生成以及增强腹腔巨噬细胞吞噬功能,而且对肝肾组织影响较小。结论 BG粗品具有较好地增强小鼠机体免疫的功能。
Objective The effect of benzyl glucosinolate (BG) in papaya seeds on the immune activity in mice was studied. Methods The crude of BG was used as the research object.The effects of crude extract on humoral immunity,non -specific immunity,viscera index and organ morphology in mice were studied.Results The crude of BG could significantly enhance the thy- mus index,promote the production of serum hemolysin and strengthen the phagocytosis of peritoneal macrophages of mice.Furthermore,it had little effect on liver and kidney tissue.Conclusion The crude of BG had a good role in enhancing the immune function of organism.
作者
赵珂
李泽友
张芳
何梦雪
王勇
张一云
ZHAO Ke;LI Ze-you;ZHANG Fang;HE Meng-xue;WANG Yong;ZHANG Yi-yun(School of Pharmaceutical Sciences,Hainan Medical University,Haikou 571199,China;Pharmaceutical Institute of Hainan Province,Haikou 570314,China)
出处
《时珍国医国药》
CAS
CSCD
北大核心
2018年第10期2323-2326,共4页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金(81260607)
海南医学院引进人才科研启动经费(2015)
作者简介
赵珂(1991-),女(汉族),河南商丘人,海南医学院药学院助理实验师,硕士学位,主要从事药物活性成分与质量控制研究工作;通讯作者:李泽友(1973-),男(汉族),安徽金寨人,海南医学院药学院教授,博士学位,主要从事药物活性成分与质量控制研究工作.
