摘要
多不饱和脂肪酸(Polyunsaturated fatty acids,PUFA),尤其是n-6和n-3 PUFAs,不仅是人体必需营养素,在调节和预防人类疾病方面同时发挥着重要作用。n-6和n-3 PUFAs在哺乳动物细胞内不能相互转换,且是动植物细胞膜的重要组成成分,具有不同的生理功能。细胞膜多不饱和脂肪酸组成比例很大程度上由膳食决定,因此平衡膳食中n-6/n-3 PUFAs具有重要意义。本文总结了n-6和n-3 PUFAs的代谢途径和作用机制,结合临床试验,阐述了平衡n-6/n-3 PUFA的重要性。
Polyunsaturated fatty acids （PUFAs）, especially n-6 and n-3 PUFAs, are not only the body＇s essential nutri-ents, but also play an important role in the regulation and prevention of human diseases, n-6 and n-3 PUFAs can not con-vert mutually in mammalian cells ,having different physiological functions. The composition of polyunsaturated fatty acids in cell membranes is determined largely by diets, so balancing the ratio of n-6/n-3 PUFAs is very significant. This article summarizes the metabolic pathways and mechanisms of n-6 and n-3 PUFAs, and combines clinical trials, elaborating the importance of a balanced n-6/n-3 PUFAs ratio.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2014年第4期626-631,479,共7页
Natural Product Research and Development
基金
国家自然基金项目(31372325)
中国科学院亚热带农业生态研究所青年人才领域前沿项目(ISACX-LYQYQN-1104)
作者简介
通讯作者Tel：86-532-88963253：E—mail：lifengna@isa．ac．cn
