摘要
目的观察氟尿嘧啶皮损内注射联合火针治疗跖疣的疗效。方法将91例跖疣患者随机分为对照组（45例）和治疗组（46例）。对照组将2.5%氟尿嘧啶注射液与2%利多卡因（5：1）的混合液注入疣体,每周1次,共2~3次。治疗组第1周使用氟尿嘧啶皮损内注射,方法同对照组,第2、3周采用火针酒精灯加热后点刺疣体治疗,每周1次,共2次。结果治疗组总有效率95.7%,对照组77.8%,两组总有效率比较差异有统计学意义（χ^2=6.3,P〈0.05）。治疗组痊愈率89.1%,对照组68.9%,两组痊愈率比较差异有统计学意义（χ^2=5.6,P〈0.05）。半年后随访,治疗组痊愈41例中有1例复发,占2.4%。对照组痊愈31例中有5例复发,占16.1%。两组复发率比较差异有统计学意义（χ^2=4.3,P〈0.05）。结论氟尿嘧啶皮损内注射联合火针治疗跖疣疗效高、不良反应少、复发率低。
Objective To investigate the clinical effect of fire needle therapy combined with local injection of Fluorouracil on plantar wart. Methods A total of 91 patients with plantar wart were randomly divided into treatment group （n = 46） and control group （n = 45 ）. The control group was given 2.5% Fluorouracil combined with 2% lidocaine （5 ： 1 ） by injection once a week for 2 - 3 times. The treatment group was treated with local injection of Fluorouracil in the first week, then treated with fire needle therapy once a week in the next two weeks. Results The total effective rate in treatment group was 95.7%, compared with 77.8% in control group. There was a significant difference between the two groups （X^2 = 6.3, P 〈 0.05 ）. The cure rates of treatment group and control group were 89.1% and 68.9% , respectively. And there was significant difference between the two groups （X^2 = 5.6, P 〈 0.05 ）. A half- a - year follow - up study showed that the recurrent rate was 2.4% in treatment group, and 16. 1% in the control group. And significant difference was observed between these two groups in the recurrent rate （ X^2 = 4.3, P 〈 0.05 ）. Conclusion Fire needle therapy combined with local injection of Fluorouracil on plantar wart is effective, with lower recurrence and adverse reaction.
出处
《安徽医学》
2011年第5期643-645,共3页
Anhui Medical Journal
关键词
火针
氟尿嘧啶
跖疣
治疗
Fire needle
Fluorouracil
Plantar wart
Therapy
