摘要
溃疡性结肠炎是一种常见的慢性肠道疾病,近年来发病呈上升趋势,而其发病机制目前尚不明确,目前认为与多种因素有关。其中免疫异常被认为是该病发病的重要因素,主要包括自身抗体、细胞免疫、细胞因子、环氧合酶与基质金属蛋白酶、氧自由基和一氧化氮等。但是遗传因素,感染因素,精神因素,饮食因素等均在其发生和发展中亦起着一定作用。本文就溃疡性结肠炎发病机制的各种影响因素予以综述。
Ulcerative Colitis is a chronic inflammatory disease of the gastrointestinal tract. The morbidity of the disease has increased in recent years while the precise etiology of it remains unknown. Now many factors are thought to be associated with it. Immune system is very important. Following factors, such as antibodies, immune cells, cytokines, COX and MMP, O2- and NO, play a key role in the pathogenesis of this disease. But it is all related to Ulcerative Colitis that genetic factors, infectious factor, psychic factor and diet factor. This article reviewed these influence factors about the etiology of ulcerative colitis.
出处
《现代生物医学进展》
CAS
2010年第16期3160-3165,共6页
Progress in Modern Biomedicine
作者简介
赵曼（1974-），女，硕士研究生，主要研究方向：消化系统疾病的诊断治疗电话：15199146527，E—mail：chywzhm@sina．com．cn
通讯作者：高峰，E-mail：xjgf@sina．com．
