摘要
目的比较奥沙拉嗪和柳氮磺吡啶(SPAP)治疗溃疡性结肠炎(UC)的有效性及安全性。方法将来74例UC患者,随机分为观察组和对照组各37例,治疗组应用奥沙拉嗪,对照组使用SPAP治疗,观察两组疗效和不良反应。结果治疗组患者的总有效率显著高于对照组,差异有统计学意义(P<0.05);治疗组不良反应发生率为5.41%,低于观察组的27.03%,差异有统计学意义(P<0.05)。结论奥沙拉嗪是治疗UC安全、有效的药物,不良反应少,值得临床推广。
Objective To compare the curative effect and untoward reaction of olsalazine and sulfasalazine（SASP） on ulcerative colitis. Methods 74 patients with ulcerative colitis were randomly divided into two groups. Patients in the treatment group were treated with olsalazine sodium capsule, which in the control group were treated with sulfasalazine tablets. The effective rate and the complications were compared, Results In comparison with the control group, total effective rate in the treatment group was significantly higher（P〈0.05）, the complication rate were lower in the treatment group（P〈0.05）. Conclusion Olsalazine is a safe and efficient drug on ulcerative colitis and has less side effects, it is worthy of clinical application.
出处
《中国医药指南》
2011年第36期279-280,共2页
Guide of China Medicine
