摘要
利用旋转涂布法在镁合金表面构建了由聚乙烯亚胺(Polyethyleneimine,PEI)、明胶(Gelatin,Gel)和硝酸铈(Cerium nitrate)组成的抗腐蚀性铈多层膜。采用接触角测试仪表征了铈多层膜在镁合金表面的组装过程;利用电化学交流阻抗图谱和极化曲线研究了铈多层膜修饰的镁合金在0.14mol/LNaCl溶液中的抗腐蚀性能;以MTT和碱性磷酸酶考察了铈多层膜修饰镁合金的细胞相容性。结果表明,在镁合金表面形成了铈多层膜结构,铈多层膜表面处理提高了镁合金的抗腐蚀性能和细胞相容性。该表面处理为镁合金植入体的应用提供了新思路。
It is fabricated that corrosion resistant cerium multilayered films composed of consisted of PEI, Gel and Ce onto magnesium alloy surfaces via a spin-assisted layer-by layer（LbL） technique. The assembly process of cerium muhilayer on magnesium alloy substrate is characterized by contact angle meter. The corrosion resistance of ceium multilayered magnesium alloy is investigated by electrochemical impedance spectroscopy（EIS） and potentiodynamic polarization measurement （TAFEL） in 0. 14mol/L NaCl solution, respectively. Cytocompatibility of cerium multilayered magnesium alloy is investigated by MTT assay and alkaline phosphatase（ALP） measurements. The results show that cerium multilayered structure is successfully formed onto the surface of magnesium alloy substrates. Such surface modification improves the corrosion resistance and cytocompatibility of magnesium alloy substrates. This surface treatment provides potential alternative for the application of magnesium alloy based implant.
出处
《材料导报》
EI
CAS
CSCD
北大核心
2010年第16期53-56,共4页
Materials Reports
基金
重庆市自然科学基金重点项目(CSTC2007BA4004)
关键词
镁合金
旋转涂布法
铈多层膜
抗腐蚀性能
细胞相容性
magnesium alloy, spin-assisted layer-by layer（LbL） technique, cerium multilayer, corrosion resistance, cytocompatibility
作者简介
睢晓静：女，1980年生，硕士，研究方向为细胞与生物材料
蔡开勇：通讯作者，教授，博士生导师，研究方向为生物材料 Tel：023-65102577 E-mail：Kaiyong_cai@cqu．edu．cn
