摘要
目的探讨甲状旁腺良性肿瘤合并甲状旁腺功能亢进的临床表现、诊治方法。方法回顾性分析本院2001年12月～2005年11月收治的30例甲状旁腺良性肿瘤合并甲状旁腺功能亢进症患者的临床资料。结果30例患者28例手术治疗,病理证实为甲状旁腺腺瘤。发病年龄15～79岁,女性多于男性,临床表现多样,年龄跨度大,病程迁延,误诊率较高。全组均表现为不同程度的骨病变及血钙明显增高。手术患者均经超声、CT及骨扫描定位,手术方式以甲状腺部分切除加甲状旁腺腺瘤切除或单纯甲状旁腺腺瘤切除为主,手术成功率100%,手术后所有症状均有不同程度的缓解,化验指标恢复正常,无喉返神经损伤等并发症发生。结论对甲状旁腺良性肿瘤合并甲状旁腺功能亢进症患者早期诊断,早期进行有效的病灶切除治疗,可减少严重骨病变的发生,减少致残率。
Objective To investigate the different clinical behavior and the diagnosis and treatment of parathyroid adenoma combined with primary hyperpara thyroidism. Methods Clinical data of 30 patients with parathyroid adenoma combined with primary hyperpara thyroidism treated from Dec 2001 to Nov 2005 were collected and analyzed. Results 28 patients with parathyroid adenoma combined with primary hyperpara thyroidism were confirmed by operation and pathology.The patients were aged 20-50years.There were more female than male patients.There were various clinical manifestations,and the duration of illness was protracted.Many cases were misdiagnosed.There were bone pathologic changes of varying extent in all patients and increasing of serum level of calcium.Ultrasound,MIBI and CT were done before operation,and accurate preoperative localization diagnosis was obtained.Minimally invasive parathyroidectomy was successfully completed and the primary operation cure rate was 100%.At postoperative the symptoms and signs were all relieved to varying extents,the laboratory markers returned to normal,and there was no permanent hypoparathyroidism or recurrent nerve injury or other complications. Conclusion Early diagnosis of parathyroid adenoma combined with primary hyperpara thyroidism and effective early treatment by surgical removal of the pathologic lesion can alleviate the occurrence of severe bone changes and deformity.
出处
《中国现代医药杂志》
2009年第6期47-48,共2页
Modern Medicine Journal of China
作者简介
通讯作者：王宁，电子邮箱：aning0516@hotmail．com
