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脂肪细胞型脂肪酸结合蛋白与动脉粥样硬化的研究进展 被引量：3

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摘要 动脉粥样硬化与代谢和炎症反应异常密切相关。脂肪细胞型脂肪酸结合蛋白作为脂肪酸结合蛋白家族中的一员,与动脉粥样硬化、代谢综合征等代谢相关疾病关系密切,成为近来研究的热点。本文就脂肪细胞型脂肪酸结合蛋白的主要特性及其与动脉粥样硬化的关系研究进展作一简要综述。
作者 金静 彭道泉
机构地区 中南大学湘雅二医院心血管内科
出处 《中国动脉硬化杂志》 CAS CSCD 北大核心 2009年第4期327-330,共4页 Chinese Journal of Arteriosclerosis
关键词 动脉粥样硬化 冠心病 脂肪细胞型脂肪酸结合蛋白
分类号 R5 [医药卫生—内科学]
作者简介 金静，硕士研究生，研究方向为心血管内科与动脉粥样硬化，E-mail为kimking06@sohu.com。 通讯作者：彭道泉，博士，教授，硕士研究生导师，研究方向为心血管内科与动脉粥样硬化，E-mail为pengdq@hotmail.com。
  • 相关文献

参考文献24

  • 1Hotamisligil GS. Inflammation and metabolic disorders [ J ]. Nature, 2006, 444 (7121) : 860 - 867,
  • 2Chmurzynska A. The muhigene family of fatty acid binding protein ( FAB-Ps) : Fuction, structure and polymorphism [ J ]. J Appl Genent, 2006, 47 (1) : 39-48.
  • 3卫超,杨为民,叶章群.膀胱移行细胞癌脂肪细胞型脂肪酸结合蛋白的表达及其意义[J].临床泌尿外科杂志,2008,23(1):65-66. 被引量：8
  • 4Shum BO, Mackay CR, Gorgun CZ, et al. The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation [J]. J Clin lnvest, 2006, 116 (8) : 2 183-192.
  • 5Xu Y, lyengar S, Roberts RL, et al. Primary culture model of peroxisome proliferators activated receptor gamma activity in prostate cancer ceils [J]. JCeUPhysiol, 2003, 196 (1) : 131-143.
  • 6Perrella MA, Penacani A, Layne MD, et al. Absence of adipocyte fatty acid binding protein prevents the development of accelerated atherosclerosis in hypercholesterolemic mice [ J ]. FASEB J, 2001, 15 ( 10 ) : 1 774- 776.
  • 7Hotamisligil GS, Johnson RS, Distel R J, et al. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein [J]. Science, 1996, 274 (5291) : 1 377-379.
  • 8Makowski L, Boord JB, Maeda K, et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis [ J ]. Nat Med , 2001,7 (6) : 699-705.
  • 9Layne MD, Patel A, Chen YH, et al. Role of macrophage-expressed adipocyte fatty acid binding protein in the development of accelerated atherosclerosis in hypercholesterolemic mice [ J ]. FASEB J, 2001, 15 (14) : 2 733-735.
  • 10Boord JB, Maeda K, Makowski L, et al. Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia [ J ]. Arterioscler Thromb Vasc Biol, 2002, 22 (10) : 1 686-691.

二级参考文献6

  • 1Reese-Wagoner A J,Thompson , Banaszak L. Structural properties of the adipocyte lipid binding protein[J]. Biochimica et Biophysica Acta, 1999, 1441(2-3):106-116.
  • 2Schaap F G, wan der Vusse G J,Glatz J F. Evolution of the family of intracellular lipid binding proteins in vertebrates[J]. Mol cell Biol, 2002, 22(14):5114-5127.
  • 3Ohlsson G, Moreira J M, Gromov P, et al. Loss of expression of the adipocyte-type fatty acid-binding protein (A-FABP) is associated with progression of human urothelial carcinomas[J]. Mol Cell protemics, 2005, 4 (4) :570-581.
  • 4Agata Chmurzyska. The multigene family of fatty acidbinding proteins (FABPs) :Function, structure and polymorphism[J]. J Appl Genent, 2006, 47( 1 ) : 39- 48.
  • 5Xu Y, Lyengar S, Roberts R L, et al. Primary culture model of peroxisome proliferators-activated receptor gamma activity in prostate cancer cells[J]. J Cell Physiol, 2003, 196(1): 131-143.
  • 6De Santis M L, Hammamieh R, Das R, et al. Adipocyte-fatty acid binding protein induces apoptosis in DU145 prostate cancer cells [J]. J Exp Ther Oncol, 2004, 4 (2):91-100.

共引文献7

同被引文献71

  • 1王宁,谢自敬,阿布力克木.吐尔地,李新岩,卢雪玲.糖尿病大鼠动脉粥样硬化与游离脂肪酸表达的关系[J].中国动脉硬化杂志,2005,13(5):563-566. 被引量：10
  • 2van der Vusse GJ, van Bilsen M, Glatz JF, et al. Critical steps in cellular fatty acid uptake and utilization [J]. Mol Cell Biochem, 2002, 239(1): 9-15.
  • 3Apple FS, Wu AH, Mair J, et al. Future biomarkers for detection of ischemia and risk stratification in acute coro- nary syndrome[J]. Clin Chem, 2005, 51(5): 810-824.
  • 4Kleinfeld AM, Prothro D, Brown DL, et al. Increases in serum unbound free fatty acid levels following coronary an- gioplasty[Jl. Am J Cardiol, 1996, 78(12) : 1 350-354.
  • 5Kleinfeld AM, Kleinfeld KJ, Adams JE. Serum levels of unbound free fatty acids reveal high sensitivity for early de- tection of acute myocardial infarction in patients samples from the TIMI II trial [ J ]. J Am Coil Cardiol, 2002, 39 ( 1 ) : 312A.
  • 6Apple FS, Kleinfeld AM, Adams J. Unbound free fatty acid concentrations are increased in cardiac ischemia[ J ]. Clin Proteomics, 2004, 1 ( 1 ) : 41-44.
  • 7Jouven X, Charles MA, Desnos M, et al. Circulating non- esterified fatty acid level as a predictive risk factor for sud- den death in the population [J].Circulation, 2001, 104 (7) : 756-761.
  • 8Richieri GV, Kleinfeld AM. Unbound free fatty acid levels in human serum[Jl. J Lipid Res, 1995, 36(2): 229- 240.
  • 9Orak M, Ustiinda g M, Gtilo glu C et al. The role of the heart-type fatty acid binding protein in the early diagnosis of acute coronary syndrome and its comparison with tropo- nin I and creatine kinase-MB isoform [ J]. Am J Emerg Med, 2010, 28(8): 891-896.
  • 10Kim KS, Lee HJ, Kim K, et al. Heart-type fatty acid binding protein as an adjunct to cardiac troponin-I for the diagnosis of myocardial infarction[ J]. J Korean Med Sci, 2011, 26(1) : 47-52.

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二级引证文献10

中国动脉硬化杂志
2009年 第4期

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