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膀胱移行细胞癌脂肪细胞型脂肪酸结合蛋白的表达及其意义 被引量:8

The expression and significance of FABP protein in bladder carcinoma tissue
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摘要 目的:探讨脂肪细胞型脂肪酸结合蛋白(A-FABP)在膀胱癌组织中的表达及其与膀胱癌的病理分级和临床分期的关系。方法:应用免疫组织化学方法检测A-FABP在43例膀胱癌组织和9例正常膀胱组织中的表达。结果:43例膀胱癌组织中A-FABP阳性表达率为72.1%,A-FABP在浸润型膀胱癌与浅表型膀胱癌组织中的表达差异有统计学意义(P<0.05)。其表达与肿瘤的临床分期及病理分化程度有较好的对应关系。结论:A-FABP蛋白的表达特征可以作为反映膀胱癌的生物学行为和预后的参考指标。 Objective:To study the Expression of FABP protein in bladder carcinoma and its significance. Methods:The expression of FABP was detected in 43 cases of bladder carcinoma by immunohistochemistry technique (SABC method). Results: The positive rate of FABP was 72. 1% in 43 cases of bladder carcinoma. The expression of FABP correlate well with their clinical stage and degree of pathologic differentiation (P〈0. 05). Conclusions: The expression of FABP protein may reflect the biological behavior and prognosis of bladder carcinoma.
出处 《临床泌尿外科杂志》 2008年第1期65-66,共2页 Journal of Clinical Urology
关键词 膀胱肿瘤 肿瘤标志物 免疫组织化学 Bladder neoplasm FABP Immunohistochemistry
作者简介 [通讯作者]卫超(E-mail:tjweichao@sina.com)
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同被引文献81

  • 1胡振兴,乔杰,李美芝,张小为,陈咏健,李蓉,孙春玲.多囊卵巢综合征相关基因的差异表达研究[J].北京大学学报(医学版),2004,36(6):600-604. 被引量:25
  • 2胡卫红,乔杰,李蓉,王丽娜.多囊卵巢综合征患者血清脂肪型脂肪酸结合蛋白水平与性激素及血脂的相关性研究[J].中华医学杂志,2006,86(45):3186-3189. 被引量:9
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