摘要
目的 探讨食管癌术后局部区域复发放射治疗的疗效和预后因素.方法 食管癌术后局部区域复发71例,其中锁骨上区复发28例,纵隔复发27例,锁骨上区加纵隔复发10例,纵隔加吻合口复发6例.全组均行放射治疗,剂量40～75 Gy.结果 全组中位生存时间13个月,1、3、5年生存率分别为49.3%（35/71）、22.5%（16/71）和8.5%（6/71）.预后因素分析结果提示术后复发时间（P＜0.05）,放射治疗剂量（P＜0.05）及肿瘤大小（P＜0.05）与患者预后密切相关.结论 食管癌术后局部复发放射治疗是首选治疗方法,放射治疗剂量应在55 Gy以上.
Objective Study the curative effects and prognostic factors about radiotherapy of local-recrudescence after resection of esophageal carcinoma. Methods From June 1987 to June 1992,71 such patients were treated by radiotherapy;in which 28 cases are recrudescence in the supra-clavicle, 27 cases in the mediastinum, 10 cases in mediastinum plus supra-clavicle, and 6 cases in mediastinum plus anastomoses-orifice. A total dose of 40～75Gy was given. Results The medium survival was 13 months and the 1-, 3-and 5 year survival rates were 49.2 %, 22.5 % and 8.5 %. The prognostic factor analysis suggests that recrudescence-time, radiotherapy dose and the size of tumours closely relate to prognostic factor. Conclusion Among the various methods of treating loco-regional recurrence after surgery of esophageal carcinoma, commonly yielding poor results, radiotherapy is still the method of choice. Doses higher than 55Gy are suggested.
出处
《实用癌症杂志》
2006年第2期173-174,179,共3页
The Practical Journal of Cancer
关键词
食管肿瘤
肿瘤复发
局部
放射疗法
预后
Esophageal neoplasm
Neoplasm recurrence, Local
Radiotherapy
Prognoses
