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食管癌术后吻合口复发因素和防治 被引量:2

The Factors of Anastomotic Recurrence(After Radical Resection of Esophageal Carcinoma) and Treatment Strategy
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摘要 探讨食管癌根治术后吻合口复发的因素,根据复发类型采取不同的治疗手段,以期降低其复发率.以21例食管癌根治术病理切缘阴性而在术后3~33个月内发现吻合口复发患者的临床资料进行回顾性分析.分别比较不同的临床分期、病理类型、手术方式、术后辅助放疗后的复发率,统计学分析用卡方检验.食管癌术后吻合口复发与肿瘤的恶性程度高、期别晚及手术范围不足等因素相关.术后纵隔区放射治疗未见改善吻合口复发的发生率.复发后适宜地采取手术或放射治疗,可以使少部分病人获益. The factors of anastomotic recurrence after radical resection of esophageal carcinoma for reducing recurrence have been appraised. The opportunity of treatment and the strategy applied depend upon different clinical stage. 21 patients, who had negative margin but later showed positive margin after resection of esophageal carcinoma, were reviewed from January 1991 to May 2001. The recurrent rates were compared according to their different clinical stages, pathological types and resection methods applied,the comparison also based on radiotherapy after operation. The Chi-Square test was used for conducting the statistic analysis. The anastomotic recurrence was clearly affected by the degree of maligrancy and the stage of the tumor,operation was not found to he sufficient , and radiotherapy could not prolong the disese-free period as well. Nevertheless,treatment such as operation or radiotherapy against anastomotic recurrence has shown improvements in a number of patients.
出处 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2006年第1期146-148,共3页 Journal of Xiamen University:Natural Science
关键词 食管癌 复发 因素 治疗 esophageal carcinoma recurrence factor treatment
作者简介 洪明(1959-),男,副主任医师.E-mail:honglan671@yahoo.com
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