摘要
目的评价前列欣胶囊治疗ⅢA型前列腺炎伴弱精子症的有效性及安全性。方法采用单中心开放性临床试验方法,对60例ⅢA型前列腺炎伴弱精子症的患者进行为期8周的观察,口服前列欣胶囊,每天3次,每次6粒。比较治疗前后患者NIH-CPSI、EPS检查、精液常规分析以及精浆酸性磷酸酶、柠檬酸的变化,并记录治疗过程中的不良反应。结果经过8周的治疗,患者NIH-CPSI评分、EPS中WBC计数显著下降;精子活力、精浆酸性磷酸酶以及精浆柠檬酸均显著上升。治疗过程中,有4例出现轻度胃部不适,未发现其他不良反应。结论前列欣胶囊可明显改善ⅢA型前列腺炎患者的症状,同时可改善患者的精子活力,恢复前列腺的功能,治疗效果确切,耐受性良好。
Objective to evaluate the efficacy and safety of Qianliexin capsule in the treatment of NIH category ⅢAprostatitis combined with asthenospermia. Methods 60 patients with NIH category ⅢA prostatitis and asthenospermia were enrolled in the trial. For each patient 6 Qianliexin capsules were orally administered 3 times a day for 8 weeks. Before and after treatment, NIH-CPSI, EPS Routine, sperm analysis, seminal plasma acid phosphatase and citrate and side effects were determined. Results After 8-week therapy, NIH- CPSI scores were significantly decreased. WBC counts in the EPS were significantly decreased. The sperm motility, seminal plasma acid phosphatase and citrate were also significantly improved. Condusion Qianliexin capsule is effective and safe in relieving the subjective symptoms and improving the objective evaluation in the treatment of NIH category ⅢA prostatitis combined with asthenospermia.
出处
《中国男科学杂志》
CAS
CSCD
2005年第5期43-45,共3页
Chinese Journal of Andrology