摘要
目的观察半密闭地下环境对健康的影响。方法于2003年9月在某半密闭地下环境中对12名健康男性受试者进行为期6d的试验观察,监测受试地下房间气温、相对湿度及风速,空气中可吸入颗粒物(IP)、CO2浓度、空气细菌总数、真菌数。分别于实验前12h(简称实验前)、进驻后第6天(简称实验中)、实验结束后第4天(简称实验后)、实验结束后第8天及第70天测定受试者血常规、体液免疫和细胞免疫指标并对受试人员饮食、饮水、睡眠、排便等基本生活规律及自觉症状进行问卷调查。结果半密闭环境平均气温15.2℃,气湿75.5%,风速0.06m/s。由于不能通风,实验中空气污染加重,空气中IP和CO2浓度分别是本底的5.1、1.6倍,细菌总数及真菌数分别是本底的7.7、3.8倍,1例受试者的白细胞计数及3例受试者的淋巴细胞偏高。实验中细胞免疫指标CD3+、CD8+及B细胞明显降低,平均分别为60.05%,26.04%及10.41%,与实验前、后比较,差异均有统计学意义(P<0.05);NK细胞(28.83%)与实验前、后比较均升高,且均有统计学意义(P<0.05)。体液免疫指标全部正常。50%以上受试者有头昏、头痛、关节痛及胸闷等自觉症状,脱离半密闭地下环境后1～4d绝大多数症状消失,而关节痛消失缓慢。结论受试者在半密闭地下环境6d内,机体代偿功能正常,无明显健康变化。
Objective To observe the effect of underground part-obturated environment on human health. Methods 12 testees were chosen to undergo the experiment of 6 days in the part-obturated situation. The microclimate blood routine immunological items and the symptoms were investigated. Results In the part-obturated environment the average temperature was 15.2 ℃ the humidity was 75.5% the velocity of the wind was 0.06 m/s. Among the testees one was found had higher WBC number three had higher lymphocytes number. During the experiment the average value of CD3+ CD8+ and B cell were 60.05% 26.04% and 10.41% respectively the NK cell was higher compared with the controlbefore the experiment the differences were significant P<0.05. The other indexes were normal. About half of the human had swirl headache and arthrosis. Because of the low temperature high humidity shadowiness and bad ventilation most testees have some symptoms in levels which disappeared after left the situation 1-4 days but the arthrosis disappeared slowly. Someone have the pharyngitis and catch a cold whose WBC and the lymphocyte number are higher than the normal. Conclusion A part of people have the normal compensation function though the cell immunological item changed. It seemed no obvious harm for human health to stay in the part-obturated environment for 6 days.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2005年第4期271-273,共3页
Journal of Environment and Health
基金
北京军区科研课题(02A004)
关键词
空气污染
室内
地下环境
健康效应
Air pollution indoor Underground environment Health effects
