摘要
目的:探讨张力平衡针法对脑梗死患者(RCI)血清白细胞介素-1(IL-1)和可溶性细胞间黏附分子-1(sICAM-1)、可溶性血管细胞黏附分子-1(sVCAM-1)含量的影响。方法:选择RCI患者82例,采用张力平衡针法与传统针法进行对照,并采用酶联免疫吸附法(ELISA)测定患者血清IL-1和sICAM-1、sVCAM-1含量的变化。结果:RCI患者IL-1及sICAM-1、sVCAM-1的水平显著高于健康组(P<0.05),且sICAM-1、sVCAM-1均与IL-1呈正相关(r=0.743,P<0.001;r=0.862,P<0.001)。两组对3项指标均有一定的改善作用,张力平衡针法组优于传统针刺组(P<0.01)。结论:张力平衡针法改善神经功能的作用可能与降低IL-1及sICAM-1、sVCAM-1的水平有关。
Objective To observe effects of acupuncture on serum interleukin-1 (IL-1) and soluble intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) in the patient of cerebral infarction. Methods Eighty-two cases of cerebral infarction were randomly divided into a treatment group treated by balanced muscular tension needling method, and a control group by traditional needling method. The levels of serum IL-1, sICAM-1 and sVCAM-1 were determined with enzyme-linked immunosorbent assay (ELISA). Results The levels of serum IL-1, sICAM-1 and sVCAM-1 in the patient of cerebral infarction were significantly higher than those in the healthy persons (P<0. 01); there were positive correlation between sICAM-1 or sVCAM-1 level and IL-1 level (r = 0. 743, P<0. 001;r = 0. 862, P<0. 001). The three indexes improved to a certain extent in the two groups, with the treatment group superior to the control group (P<0. 01). Conclusion The improvement of nervous function by the balanced muscular tension needling method in the patient of cerebral infarction is possibly related with decrease of IL-1, sICAM-1 and sVCAM-1 levels.
出处
《中国针灸》
CAS
CSCD
北大核心
2005年第3期214-216,共3页
Chinese Acupuncture & Moxibustion
基金
国家中医药管理局中医临床诊疗技术整理与研究项目:2001ZL36
