摘要
Eurycoma longifolia,also known as Tongkat Ali in Malaysia,as one of traditional herbal medicines,is used for centuries in South-East Asia.With the discovery of anticancer and anti-HIV properties,this herbal medicine has attracted great attention recently.In this review,the following information on E.longifolia,including chemistry,bioactivities,pharmacokinetics,clinical studies,and side effects and safety,was introduced.Our results,to a certain extent,will provide scientific base for commercial utilization and clearance of the Tongkat Ali products with regard to consumers’ safety.
Eurycoma longifolia,also known as Tongkat Ali in Malaysia,as one of traditional herbal medicines,is used for centuries in South-East Asia.With the discovery of anticancer and anti-HIV properties,this herbal medicine has attracted great attention recently.In this review,the following information on E.longifolia,including chemistry,bioactivities,pharmacokinetics,clinical studies,and side effects and safety,was introduced.Our results,to a certain extent,will provide scientific base for commercial utilization and clearance of the Tongkat Ali products with regard to consumers' safety.
作者
HOU Wen-bin1,2,3,XIAO Xue-feng1,GUO Wei4,ZHANG Tie-jun2,3 1.Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China 2.Research Center for Modern Chinese Materia Medica,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 3.State Key Laboratory of Drug Delivery Technology and Pharmacokinetics,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 4.Xiehe Pharmaceutical Group Company,Shenyang 110179,China
基金
Major Scientific and Technological Special Project "Significant New Drugs Creation" of China (2009ZX09304-005)
National Basic Science Plan (973Plan) (2010CB735602)