摘要
目的观察联合应用血液灌流、血液透析和长托宁治疗重症有机磷中毒疗效。方法将40例重度有机磷农药中毒患者分为治疗组(联合应用血液灌流、血液透析和长托宁治疗)和对照组(常规治疗组)。对照组按常规予积极洗胃、导泻催吐,并予阿托品及氯磷定治疗。治疗组在常规治疗基础上联合应用血液灌流、血液透析和长托宁治疗。观察ChE恢复时间、长托宁和阿托品用量和给药次数、机械通气时间、昏迷时间、死亡率等指标。结果治疗组ChE恢复时间、长托宁用量和给药次数、机械通气时间、昏迷时间、死亡率均显著低于对照组(P<0.05)。结论联合应用血液灌流、血液透析和长托宁治疗重症有机磷中毒疗效显著。
Objective To observe the efficacy of the hemoperfusion?hemodialysis and the penehyclidine hydrochloride injection in the treatment of the patients with acute servere organophosphorus pesticide poisoning. Methods 40 patients with acute servere organophosphorus pesticide poisoning were divided into the theropy group (treat with hemoperfusion?hemodialysis and the penehyclidine hydrochloride ) and the control group ( traditional treatment group). The control group were only accepted the traditional treatment including gastric lavage?catharsis? emetic? atropine and pyraloxime chloride. The theropy group were accepted hemoperfusion?hemodialysis and the penehyclidine hydrochloride on the base of traditional treatment.To observe the duration of the recovery of cholinesterase activity, the cumulative dosages and frequency of the penehyclidine hydrochloride injection and atropine,the duration of mechanical ventilation and unconscious ,the mortality. Results The theropy group, s duration of the recovery of cholinesterase activity?the cumulative dosages and frequency of the penehyclidine hydrochloride and atropine,the duration of mechanical ventilation and unconscious?the mortality are lower than those of the control groups. Conclusion The hemoperfusion?hemodialysis and the use of penehyclidine hydrochloride injection are effective in the treatment of the patients with acute servere organophosphorus pesticide poisoning.
出处
《中国医药导报》
CAS
2006年第32期27-29,共3页
China Medical Herald
关键词
血液灌流
血液透析
长托宁
有机磷农药中毒
hemoperfusion
hemodialysis
penehyclidine hydrochloride
organophosphorus pesticide poisoning
