摘要
目的研究中西医结合疗法预防椎体转移瘤患者放疗爆发痛的临床效果.方法选取2020年1—12月该院收治的椎体转移瘤患者98例,按照随机数字表法分为两组,每组49例.对照组给予常规癌痛三阶梯镇痛治疗,试验组在对照组基础上联合自拟中药解毒定痛方口服治疗,疗程为4周.于治疗前,治疗第28天、治疗结束后30 d,分别应用疼痛视觉模拟评分法(VAS)评估两组患者疼痛程度,比较两组患者疼痛缓解效果及中医证候疗效.结果治疗第28天、治疗结束后30 d,试验组VAS评分均明显低于对照组,组间差异有统计学意义(P<0.05).试验组疼痛缓解总有效率95.92%明显高于对照组的77.55%,差异有统计学意义(P<0.05).试验组中医证候总有效率89.80%明显高于对照组的73.47%,差异有统计学意义(P<0.05).结论中西医结合治疗可有效预防椎体转移瘤放疗爆发痛,提高临床疗效.
Objective To study the clinical effect of integrated traditional Chinese and Western medicine therapy in the prevention of radiotherapy burst pain in patients with vertebral metastases.Methods A total of 98 patients with vertebral metastases admitted to our hospital from January to December 2020 were selected and divided into two groups according to the random number table method,with 49 cases in each group.The control group was given conventional three-step analgesia for cancer pain,while the experimental group was given oral treatment with the self-made Chinese medicine Jiedu Dingtong prescription on the basis of the control group,and the course of treatment was 4 weeks.On the 28th day of treatment and 30 days after the end of treatment,the pain visual analog scale(VAS)was used to evaluate the pain degree of the two groups of patients,and the pain relief effect and the effect of traditional Chinese medicine syndrome were compared between the two groups.Results On the 28th day of treatment and 30 days after the end of treatment,the VAS scores of the experimental group were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).The total effective rate of pain relief in the experimental group was 95.92%,which was significantly higher than 77.55%in the control group,and the difference was statistically significant(P<0.05).The total effective rate of TCM syndromes in the experimental group was 89.80%,which was significantly higher than 73.47%in the control group,and the difference was statistically significant(P<0.05).Conclusion Integrative traditional Chinese and Western medicine treatment can effectively prevent vertebral metastases from radiotherapy burst pain and improve clinical efficacy.
作者
刘清磊
马芹
王苗
张亮
胡志勇
张楠
LIU Qinglei;MA Qin;WANG Miao;ZHANG Liang;HU Zhiyong;ZHANG Nan(Department of Orthopedic,Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Hebei Province,Cangzhou Hebei,061000,China;Department of Radiotherapy and Chemotherapy,Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Hebei Province,Cangzhou Hebei,061000,China;Department of Internal Medicine of Traditional Chinese Medicine,Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Hebei Province,Cangzhou Hebei,061000,China)
出处
《反射疗法与康复医学》
2021年第21期1-3,7,共4页
Reflexology And Rehabilitation Medicine
基金
河北省中医药管理局课题(2020492)。
关键词
中西医结合疗法
椎体转移瘤
放疗
爆发痛
Traditional Chinese and Western medicine treatment
Vertebral metastasis
Radiotherapy
Explosive pain
作者简介
刘清磊(1984-),男,河北沧州人,硕士研究生,主治医师,研究方向:骨科常见疾病的治疗。
