摘要
目的分析柴胡龙骨牡蛎汤加减联合硝苯地平对原发性高血压(EH)肝阳上亢证患者的治疗效果.方法选取2021年4月—2023年4月该院收治的86例EH肝阳上亢证患者为研究对象,采用随机数字表法将其分为对照组和观察组,各43例.对照组采用硝苯地平治疗,观察组在对照组基础上加以柴胡龙骨牡蛎汤加减治疗,两组均持续治疗4周.对比两组临床疗效﹑中医证候评分﹑血压控制情况﹑不良反应发生情况.结果观察组治疗总有效率为95.35%,高于对照组的79.07%,差异有统计学意义(P<0.05).治疗前,两组头晕﹑头痛﹑急躁易怒﹑面红目赤评分与舒张压(DBP)﹑收缩压(SBP)水平比较,组间差异无统计学意义(P>0.05);治疗后,观察组头晕评分(1.54±0.16)分﹑头痛评分(1.16±0.15)分﹑急躁易怒评分(1.41±0.18)分﹑面红目赤评分(1.16±0.08)分﹑DBP水平(82.41±2.01)mmHg(1 mmHg=0.133 kPa)﹑SBP水平(125.97±5.63)mmHg均低于对照组的(2.30±0.28)分﹑(1.88±0.24)分﹑(2.33±0.27)分﹑(1.97±0.13)分﹑(87.64±2.59)mmHg﹑(136.45±7.40)mmHg,组间差异有统计学意义(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论柴胡龙骨牡蛎汤加减联合硝苯地平治疗EH肝阳上亢证能够降低患者血压,减轻中医证候,且无严重不良反应.
Objective To analyze the effect of Chaihu Longgu Oyster soup plus nifedipine in the treatment of patients with primary hypertension(EH)with hyperactivity of liver yang.Methods 86 patients with EH liver yang hyperactivity syndrome admitted to the hospital from April 2021 to April 2023 were selected as the research objects and they were randomly divided into a control group and an observation group,with 43 patients in each group.The control group was treated with nifedipine,and the observation group was treated with Chaihu Longgu Oyster soup for 4 weeks.Compare the clinical efficacy,traditional Chinese medicine syndrome scores,blood pressure control,and adverse reactions between the two groups.Results The total effective rate of the observation group was 95.35%,which was higher than 79.07%of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference between the two groups in terms of dizziness,headache,irritability,redness,and redness scores,as well as diastolic blood pressure(DBP)and systolic blood pressure(SBP)(P>0.05);after treatment,the dizziness score(1.54±0.16)points,headache score(1.16±0.15)points,irritability score(1.41±0.18)points,redness score(1.16±0.08)points,DBP level(82.41±2.01)mmHg(1 mmHg=0.133 kPa),and SBP level(125.97±5.63)mmHg in the observation group were all lower than(2.30±0.28)points,(1.88±0.24)points,(2.33±0.27)points,(1.97±0.13)points,(87.64±2.59)mmHg,and(136.45±7.40)mmHg in the control group,with statistically significant differences between groups(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Chaihu Longgu Oyster soup plus nifedipine can reduce the blood pressure of EH patients with liver yang hyperactivity syndrome and relieve TCM syndromes without serious adverse reactions.
作者
曲芳
QU Fang(Department of Cardiology,Yantai Penglai Traditional Chinese Medicine Hospital,Yantai Shandong,265600,China)
出处
《反射疗法与康复医学》
2023年第20期23-25,29,共4页
Reflexology And Rehabilitation Medicine
关键词
原发性高血压
肝阳上亢证
柴胡龙骨牡蛎汤加减
硝苯地平
Primary hypertension
Syndrome of hyperactivity of liver yang
Addition and subtraction of Chaihu Longgu Oyster soup
Nifedipine
作者简介
曲芳(1985-),女,山东烟台人,硕士研究生,主治医师,研究方向:高血压病诊疗.
