清眩降压汤联合尼莫地平对阴虚阳亢型老年高血压患者血压控制及中医证候的影响被引量：3

Effect of Qingxuan Jiangya Decoction Combined with Nimodipine on Blood Pressure Control and TCM Syndromes in Elderly Hypertensive Patients with Yin Deficiency and Yang Hyperactivity

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摘要目的探究清眩降压汤联合尼莫地平对阴虚阳亢型老年高血压患者血压控制及中医证候的影响.方法选择本院2020年3月—2021年12月收治的106例老年高血压患者为研究对象,按照随机数字表法分为对照组和观察组,每组53例.对照组采用尼莫地平治疗,观察组在对照组基础上加用清眩降压汤治疗,均持续治疗1个月.比较两组中医证候、临床疗效、血压水平以及安全性.结果治疗前,两组中医证候评分、血压比较,组间差异无统计学意义(P>0.05);观察组治疗后中医证候评分(21.10±2.05)分较对照组更低,24 h平均收缩压(116.85±6.69)mmHg、24 h平均舒张压(75.69±3.13)mmHg、白天平均舒张压(76.81±3.15)mmHg、白天平均收缩压(120.54±6.79)mmHg、夜间平均舒张压(72.11±3.16)mmHg、夜间平均收缩压(110.37±4.38)mmHg均低于对照组,组间差异有统计学意义(P<0.05).观察组治疗总有效率96.23%高于对照组的81.13%,差异有统计学意义(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论清眩降压汤联合尼莫地平治疗阴虚阳亢型老年高血压的临床效果确切,能够控制血压水平,加快中医证候改善,且安全性较高. Objective To explore the effect of Qingxuan Jiangya Decoction combined with nimodipine on blood pressure control and TCM syndromes in elderly hypertensive patients with yin deficiency and yang hyperactivity.Methods 106 elderly hypertensive patients admitted to the hospital from March 2020 to December 2021 were selected as the research objects,and divided into a control group and an observation group according to the random number table method,with 53 cases in each group.The control group was treated with nimodipine,and the observation group was additionally treated with Qingxuan Jiangya Decoction on the basis of the control group.Both groups were treated for 1 month.The TCM syndromes,clinical efficacy,blood pressure levels and safety were compared between the two groups.Results Before treatment,there was no significant difference in TCM syndrome scores and blood pressure between the two groups(P>0.05);after treatment,the TCM syndrome score of the observation group was(21.10±2.05)points,which was lower than that of the control group,the 24 hour mean systolic blood pressure,24 hour mean diastolic blood pressure,day mean diastolic blood pressure,day mean systolic blood pressure,night mean systolic blood pressure,and night mean systolic blood pressure in the observation group were(116.85±6.69)mmHg,(75.69±3.13)mmHg,(76.81±3.15)mmHg,(120.54±6.79)mmHg,(72.11±3.16)mmHg,(110.37±4.38)mmHg,which were lower than those in the control group,and the differences between the groups were statistically significant(P<0.05).The total effective rate of the observation group was 96.23%,which was higher than 81.13%of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The clinical effect of Qingxuan Jiangya Decoction combined with nimodipine in the treatment of elderly hypertension with yin deficiency and yang hyperactivity is exact,it can control the blood pressure level,accelerate the improvement of TCM syndromes,and has high safety.

作者王荣荣赵金春 WANG Rongrong;ZHAO Jinchun(Zhengjia Branch of Traditional Chinese Medicine Hospital of Dongchangfu District,Liaocheng City,Liaocheng Shandong,252000,China)

机构地区聊城市东昌府区中医院郑家院区

出处《反射疗法与康复医学》 2022年第10期11-14,共4页 Reflexology And Rehabilitation Medicine

关键词高血压阴虚阳亢型清眩降压汤尼莫地平中医证候血压安全性 Hypertension Yin deficiency and yang hyperactivity Qingxuan Jiangya Decoction Nimodipine TCM syndrome Blood pressure Security

分类号 R544.1 [医药卫生—心血管疾病]

作者简介王荣荣(1985-),女,山东聊城人,本科,主治医师,研究方向:内科临床疾病诊治。