摘要
探讨12周最大脂肪氧化(maximum fat oxidation,FATmax)运动对肥胖型非酒精性脂肪肝病(non-alcoholic fatty liver disease,NAFLD)患者血糖血脂及肝功能的影响,为NAFLD患者的康复治疗提供运动处方参考。将54名肥胖型NAFLD大学生随机分成运动组和对照组,其中运动组进行12周、每周4次的FATmax强度运动,对照组不进行任何形式的系统性体育运动。在试验前、试验后分别对两组受试者血糖、胰岛素抵抗指数、血脂4项及肝功能14项进行测试。结果显示:(1)试验后,体重(P=0.017,ES=0.856)、体脂率(P=0.043,ES=0.776)、肌肉含量(P=0.030,ES=0.781)和BMI(P=0.005,ES=1.039)均呈现出组别和时间交互作用,运动组体重(P<0.05)、体脂率(P<0.05)和BMI(P<0.01)均显著低于对照组的,而肌肉含量则显著高于对照组的(P<0.05);(2)试验后,TC(P=0.021,ES=0.929)、HDL-C(P=0.032,ES=0.747)、ALT(P=0.028,ES=0.869)、AST(P=0.048,ES=0.761)、TBIL-V(P=0.038,ES=0.810)、GGT(P=0.049,ES=0.757)均呈现出组别和时间交互作用,运动组的TC、ALT、AST、TBIL-V和GGT均显著低于对照组的(P<0.05),仅HDL-C显著高于对照组的(P<0.05)。本研究表明,12周的FATmax强度运动能显著降低肥胖型NAFLD患者的体重和体脂,改善血脂代谢异常,减轻肝功能的损伤,并能提高患者肌肉含量。
The study explored the effects of 12-week FATmax intensity exercise on blood glucose,blood lipids and liver function on obese non-alcoholic fatty liver disease(NAFLD)patients,and provided exercise prescription reference for rehabilitation of NAFLD patients.54 obese college students with NAFLD were randomly divided into exercise group and control group.The exercise group received FATmax intensity exercise intervention 4 times a week for 12 weeks,and the control group did not take any form of systematic sports.The four items of blood glucose,insulin resistance index,4 items of blood lipids and 14 items of liver function were tested before and after the test.The results are as follows:(1)After the test,body weight(P=0.017,ES=0.856),body fat percentage(P=0.043,ES=0.776),muscle content(P=0.030,ES=0.781),and BMI(P=0.005,ES=1.039)showed interaction between groups and time.The weight(P<0.05),body fat percentage(P<0.05)and BMI(P<0.01)of the exercise group were significantly lower than that of those of the control group,and the muscle content was significantly higher than the control group(P<0.05).(2)After the test,TC(P=0.021,ES=0.929),HDL-C(P=0.032,ES=0.747),ALT(P=0.028,ES=0.869),AST(P=0.048,ES=0.761),TBIL-V(P=0.038,ES=0.810),GGT(P=0.049,ES=0.757)showed inter-group and time interaction,and compared with control group,TC,ALT,AST,TBIL-V,GGT in the exercise group were significantly lower(P<0.05),HDL-C was significantly higher(P<0.05).The study indicated that 12 weeks of FATmax intensity exercise can significantly reduce body fat in obese NAFLD patients,improve blood lipid metabolism,reduce liver damage,and increase muscle mass in patients.
作者
彭永
朱欢
杨梅
周慧敏
刘晓丽
王成科
Peng Yong;Zhu Huan;Yang Mei;Zhou Huimin;Liu Xiaoli;Wang Chengke(Physical Education College,Hubei Minzu University,Enshi,445000;School of Music and Physical Education,Enshi College of Hubei,EnShi,445000;Department of Sports and Health,Guangxi Preschool Teachers College,Nanning,530000)
出处
《基因组学与应用生物学》
CAS
CSCD
北大核心
2022年第3期648-658,共11页
Genomics and Applied Biology
基金
2019年湖北省教育厅科学研究计划重点项目(Q20191901)
2020年湖北省教育厅科学技术研究项目(Q20201906)共同资助
作者简介
通信作者:王成科,wangchengke2021@yeah.net
