摘要
Non-antibiotic fungicides are urgently needed due to the potential threat of drug-resistant bacteria to human health.In this research,a novel antibacterial nanoplatform based on CeO_(2)@C-N has been developed to achieve rapid near-infrared(NIR)laser-induced sterilization.The prepared CeO_(2)@C-N hybrid material exhibited a nanowire-like structure,with dispersed CeO_(2)nanoparticles averaging 5 nm in size within the heterogeneous configuration.X-ray photoelectron spectroscopy(XPS)and Raman spectra revealed that the heterogenous structures have a significant amount of oxygen vacancies and defects.Notably,CeO_(2)@C-N has a narrower band gap than CeO_(2),which allows for broader absorbance extending to the NIR region.With these unique physiochemical properties,CeO_(2)@C-N could inactivate E.coli and MRSA at a low concentration(20 mg/L)under 808 nm NIR laser(1 W/cm^(2))irradiation.The excellent bactericidal activity of CeO_(2)@C-N is attributed to the combination of photodynamic and photo thermal processes,based on its excellent photo-thermal conversion property,detection of reactive oxygen species(ROS)(^(1)O_(2)and·OH)under light irradiation,and scavenger quenching experiment results.This study offers a feasible and efficient way to fabricate a highly effective antibacterial candidate.
基金
supported by the National Natural Science Foundation of China(21906033)
the introduced innovative R&D team project under the“The Pearl River Talent Recruitment Program”of Guangdong Province(2019ZT08L387)
the Natural Science Foundation of Guangzhou City(202102020570,202201020392)
the Depar tment of Science and Technology of Hubei Province(2019CFB365)
the Department of Education of Hubei Province(Q20192805)
作者简介
Yijun Pang,contributed equally to this work;Zhiquan Chen,contributed equally to this work;Li Zhou,zhoul@gzhu.edu.cn
