摘要
目的探讨超声造影联合粗针活检在最大径≥3.0 cm乳腺恶性病变诊断中的应用价值。方法选取自2016年9月至2021年7月在北部战区总医院超声诊断科行粗针活检的77例乳腺恶性病变患者为研究对象。所有患者均由病理证实。根据穿刺引导方式将患者分为常规超声引导组(n=41)与超声造影引导组(n=36)。常规超声引导组行超声引导下粗针穿刺活检,超声造影引导组先应用SonoVue造影后再根据灌注区域行粗针穿刺活检。比较两组患者的粗针活检诊断成功率。结果所有患者均取材满意,未发生严重并发症。64例患者获得明确的组织病理学结果,诊断成功率为83.1%(64/77)。常规超声引导组在较大乳腺病灶粗针活检中的诊断成功率为75.6%(31/41),低于超声造影引导组的91.7%(33/36),差异有统计学意义(P<0.05)。结论超声造影可对乳腺病灶内的血供情况更好地评估,判断病灶内部活性区域,提高最大径≥3.0 cm乳腺恶性病变粗针活检诊断成功率,因此在粗针穿刺活检中有较高的应用价值。
Objective To evaluate the value of contrast-enhanced ultrasound combined with thick needle biopsy in the treatment of malignant breast lesions with a maximum diameter of≥3.0 centimeters.Methods From September 2016 to July 2021,77 patients with malignant breast lesions who underwent coarse needle biopsy in the department of ultrasound of General Hospital of Northern Theater Command were selected as the research subjects.All patients were confirmed by pathology.Patients were divided into conventional ultrasound guided group(n=41)and contrast-enhanced ultrasound guided group(n=36)according to the puncture guidance method.The conventional ultrasound guided group received ultrasound-guided coarse needle biopsy,while the contrast-enhanced ultrasound guided group received SonoVue angiography first and then received coarse needle biopsy according to the perfusion area.The diagnostic success rate of coarse needle biopsy was compared between the two groups.Results All patients were satisfied with sampling and no serious complications occurred.A total of 64 patients obtained definite histopathological results,and the diagnostic success rate was 83.1%(64/77).The positive rate of pathological diagnosis in conventional ultrasound guided thick needle biopsy in large malignant breast lesions was 75.6%(31/41),which was lower than that of conventional ultrasound guided group 91.7%(33/36),P<0.05.Conclusion Contrast-enhanced ultrasonography can better evaluate the blood supply and distinguish the internal necrotic areas of malignant breast lesions with a maximum diameter of≥3.0 centimeters,which can improve the accuracy of puncyure pathological diagnosis,and has high clinical value in thick needle biopsy of large malignant breast lesions.
作者
里子彧
曹军英
牟泳霖
张筠
LI Zi-yu;CAO Jun-ying;MU Yong-lin;ZHANG Yun(Postgraduate Training Base of General Hospital of Northern Theater Command,Jinzhou Medical University,Shenyang 110016,China;Department of Ultrasound diagnosis,General Hospital of Northern Theater Command,Shenyang 110016,China)
出处
《临床军医杂志》
CAS
2022年第7期682-684,688,共4页
Clinical Journal of Medical Officers
基金
辽宁省科学技术计划项目(2020JH2/10300122)
关键词
超声造影
粗针活检
乳腺恶性病变
Contrast-enhanced ultrasound
Thick needle biopsy
Malignant breast lesions
作者简介
第一作者:里子彧(1985-),女,辽宁沈阳人,主治医师;通信作者:曹军英,E-mail:shenzongchaosheng@163.com