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热惊厥患儿脑电图监测与后期癫痫事件发生的关系

The relationship between EEG monitoring and late epileptic events in children with febrile seizures
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摘要 目的:探讨脑电图检查对预测热惊厥患儿后期癫痫发生的诊断价值及影响因素。方法:回顾性分析我院2015年1月至2022年1月间诊治的172名热惊厥患儿,收集患者的临床资料,包括姓名、性别、年龄、既往癫痫史、热惊厥类型及次数等,分析脑电图异常组中脑电图异常率以及后期出现癫痫事件的发生率。结果:共纳入的172例临床热惊厥患儿中,脑电图正常组112例,脑电图异常组60例,男性占60%,女性占40%;单纯性惊厥占83.7%,复杂性惊厥占16.3%。脑电图慢波异常组的发生率(40%)分别高于各局灶组单独的发生率(颞叶26.7%,顶叶3.3%,中央颞部10.0%,额叶20.0%)。共有30例患儿出现癫痫,全部来自于脑电图异常组,颞叶区、顶叶区、中央颞部区、额叶区及弥漫性区脑电图患儿的癫痫发生率分别为75.0%、0%、33.3%、75.0%、25.0%。颞叶区和额叶区脑电图异常患儿的后期癫痫发生率显著高于弥漫型异常患儿。结论:脑电图检查可以用来预测和诊断热惊厥患儿后期发生癫痫,为小儿热惊厥发生癫痫的诊断和评估提供重要的参考依据。 Objective:To explore the diagnostic value and influencing factors of electroencephalogram(EEG)in predicting the occurrence of epilepsy in children with febrile seizures.Methods:172 children with febrile convulsion diagnosed and treated in our hospital from January 2015 to January 2022 were retrospectively analyzed.The clinical data of the patients were collected,including name,gender,age,previous epilepsy history,febrile convulsion type and frequency,the abnormal rate of EEG in the abnormal EEG group and the incidence of epilepsy in the later period were analyzed.Results:among 172 children with febrile convulsion,112 cases were in normal EEG group and 60 cases were in abnormal EEG group,60%of them were male and 40%were female;Simple convulsion accounted for 83.7%,and complex convulsion accounted for 16.3%.The incidence of diffuse EEG abnormality(40%)was higher than that of each focal group(temporal lobe 26.7%,parietal lobe 3.3%,central temporal 10.0%,frontal lobe 20.0%).There were 30 children with late epilepsy,all from the abnormal EEG group.The incidence of epilepsy in temporal lobe,parietal lobe,central temporal region,frontal lobe and diffuse area was 75.0%,0%,33.3%,66.7%and 25.0%respectively.The incidence of late epilepsy in children with abnormal EEG in temporal lobe and frontal lobe was significantly higher than that in children with diffuse abnormal EEG.Conclusion:EEG can be used to predict and diagnose epilepsy in children with febrile convulsion,and provide important reference for the diagnosis and evaluation of epilepsy in children with febrile convulsion.
作者 高妙 娄冬 郑娟娟 GAO Miao;LOU Dong;ZHENG Juanjuan(Department of Elctroencephalogram,Huaihe Hospital of Henan University,Kaifeng 475000,CHN)
出处 《河南大学学报(医学版)》 CAS 2023年第3期215-218,共4页 Journal of Henan University:Medical Science
基金 河南省科技攻关计划(232102310024)
关键词 脑电图 癫痫 热惊厥 EEG epilepsy febrile convulsion
作者简介 通信作者:高妙(1982-),女,主治医师。研究方向:神经电生理,E-mail:42326894@qq.com
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