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冠心病患者中医辨证分型特点及血脂指标相关性分析研究 被引量:19

Study on Characteristics of TCM Syndrome Differentiation and Correlation of Blood Lipid Index in Patients with Coronary Heart Disease
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摘要 目的探讨冠心病患者血脂指标与不同中医辨证分型的相关性,为冠心病的中医辨证分型提供参考。方法选择2018年4月—2019年10月在该院就诊的335例冠心病患者进行研究。参考患者体征、临床症状及舌脉特征对其进行中医辨证分型。其中痰阻心脉型73例、心血瘀阻型58例、气虚血瘀型54例、气滞血瘀型51例、气阴两虚型47例、阳气虚衰型32例,将6种证型设为研究组,另选择同期我院健康体检者80例为对照组。分析比较各证型患者血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)等血脂指标水平。结果研究组患者TC、TG、LDL-C水平均明显高于对照组,HDL-C水平明显低于对照组,差异有统计学意义(P<0.05)。研究组内各证型患者TC水平比较,差异有统计学意义(P<0.05);其中,痰阻心脉型TC水平均明显高于其他5种证型,差异有统计学意义(P<0.05)。研究组内各证型患者TG、HDL-C水平比较,差异无统计学意义(P>0.05)。研究组内各证型患者LDL-C水平比较,差异有统计学意义(P<0.05);其中,痰阻心脉型LDL-C水平明显高于其他5种证型,差异有统计学意义(P<0.05)。结论冠心病患者以痰阻心脉型最多,患者TC、LDL-C水平越高,越有可能辨证为痰阻心脉型,血脂指标检测对冠心病中医辨证分型有一定的参考价值。 Objective Toexplore the correlation between serum lipids and different traditional Chinese medicine(TCM)syndrome differentiation types in patients with coronary heart diseasein order to provide reference for TCM syndrome differentiation types of coronary heart disease.Methods From April 2018 to October 2019,335 cases of patients with coronary heart disease who received treatment in our hospital were collected.The patients were differentiated according to the patients′signs,clinical symptoms,tongue-pulse characteristicsand TCM syndrome.Thephlegm stagnation in heart meridian syndrome type(73 cases),blood stasisin heart syndrome type(58 cases),Qi deficiency and blood stasissyndrome type(54 cases),Qi stagnation and blood stasissyndrome type(51 cases),Qi-Yin deficiencysyndrome type(47 cases)and Yang-Qi deficiencysyndrome type(32 cases)were collected as the study groupwhile 80 cases of healthy people in our hospital health examination centerduring the same period were collected as the control group.The levels of serum total cholesterol(TC),triglyceride(TG),low-density lipoprotein-cholesterin(LDL-C)and high-density lipoprotein-cholesterin(HDL-C)were analyzed and compared in each group.Results The levels of serum TC,TG and LDL-C in the study group were significantly higher than those in the control group,while the level of HDL-C was significantly lower than that in the control group,and the differences were statistically significant(P<0.05).The TC level of each syndrome type in the study group was compared,and the difference was statistically significant(P<0.05).Among them,the TC level of phlegm stagnation in heart meridian syndrome type was significantly higher than that of the other 5 syndrome types,and the differences were statistically significant(P<0.05).There were no significant difference in TG or HDL-C levels among the patients with different syndromes in the study group(P>0.05).The level of LDL-C ofthe each syndrome type in the study group was compared,and the difference was statistically significant(P<0.05).Among them,the LDL-C level of phlegm stagnation in heart meridian syndrome type was significantly higher than that of the other 5 syndrome types,and the differences were statistically significant(P<0.05).Conclusion The most common syndrome of patients with coronary heart disease is phlegm stagnation in heart meridian syndrome,The higher the levels of TC and LDL-C in patients are,the more likely it isthe syndrome of phlegm stagnation in heart meridian,which indicates that serum lipid index has certain reference value for TCM syndrome differentiation of coronary heart disease.
作者 姜宜 李雪玲 JIANG Yi;LI Xueling(Enshi Central Hospital,Enshi 445000,Hubei,China)
机构地区 恩施州中心医院
出处 《辽宁中医杂志》 CAS 2020年第8期89-91,共3页 Liaoning Journal of Traditional Chinese Medicine
关键词 冠心病 血脂 中医证型 总胆固醇 低密度脂蛋白 相关性 coronary heart disease serum lipid traditional Chinese medicine syndrome type total cholesterol low density lipoprotein correlation
作者简介 姜宜(1970-),女,湖北恩施人,学士,研究方向:检验相关。
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