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中医辨证护理对咳嗽变异性哮喘患儿呼吸功能及炎症因子表达的影响 被引量:16

Effect of TCM Syndrome Differentiation Nursing on Respiratory Function and Expression of Inflammatory Factors in Children with Cough Variant Asthma
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摘要 目的探讨中医辨证护理对咳嗽变异性哮喘(CVA)患儿呼吸功能及炎症因子表达的影响。方法选取浙江省台州市立医院儿内科2017年1月—2019年1月间收治的CVA患者100例,采用随机数字表法将患儿分为对照组(50例)和观察组(50例)。对照组患儿给予常规护理,观察组患儿给予中医辨证护理。比较两组患者临床疗效及临床症状改善情况,干预前后血清细胞因子水平、呼吸功能。结果观察组的总有效率为96%,显著高于对照组80%;观察组阵发呛咳、痰黏难咳、大便秘结、夜卧不安及手足心热的比例显著低于对照组,差异有统计学意义(P<0.05)。干预后观察组血清IL-6、CRP及TNF-α水平均显著低于对照组,观察组FVC、FVE1及PEF显著高于对照组,差异有统计学意义(P<0.05)。结论中医辩证护理可改善咳嗽变异性哮喘患儿临床症状,提高治疗效果,同时改善患儿炎性因子水平及呼吸功能。 Objective To explore the effect of TCM syndrome differentiation nursing on respiratory function and expression of inflammatory factors in children with cough variant asthma(CVA).Methods From January 2017 to January 2019,100 patients with CVA were treated in the respiratory department of the hospital.The children were randomly divided into control group(n=50)and observation group(n=50).The children in the control group were given routine nursing,while those in the observation group were given nursing according to syndrome differentiation of traditional Chinese medicine.The clinical efficacy and improvement of clinical symptoms were compared between the two groups.The level of serum cytokine and respiratory function were compared between two groups before and after intervention.Results Compared with control group(80%),the total effective rate of the observation group was significantly higher(96%);Compared with control group,the proportion of sudden cough,phlegm sticky cough,stool secret knot,night restlessness and hand and foot heart fever in the observation group was significantly higher(P<0.05).After intervention,compared with control group,the levels of serum IL-6,CRP and TNF-αin the observation group were significantly lower,FVC,FVE1 and PEF in the observation group were significantly higher(P<0.05).Conclusion TCM dialectical nursing can improve the clinical symptoms and therapeutic effect of children with cough variant asthma,and improve the level of inflammatory factors and respiratory function in children with cough variant asthma.
作者 洪梅 高鑫 HONG Mei;GAO Xin(Department of Pediatrics,Taizhou Municipal Hospital,Taizhou 318000,China)
出处 《中国全科医学》 CAS 北大核心 2019年第S02期229-232,共4页 Chinese General Practice
关键词 中医辨证护理 咳嗽变异性哮喘 呼吸功能 炎症因子 Nursing of TCM Syndrome differentiation Cough variant Asthma Respiratory function Inflammatory factors
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