摘要
目的在中国藏汉两族2型糖尿病人群中应用瞬感扫描式动态血糖监测系统的准确性。方法选择2017年8月10日~2017年10月15日内分泌科病房收治的68例2型糖尿病患者作为研究对象,运用瞬感扫描式动态血糖监测系统为患者进行14天的动态血糖监测,同时每天在空腹和三餐后两小时采集指尖血,采用酶电极法进行指尖血糖检测,并记录采血时即刻扫描的动态血糖监测值。以指血血糖为标准,评价瞬感扫描式动态血糖监测结果(扫描血糖)的准确性,分析扫描血糖的平均相对绝对差(MARD)的影响因素。结果扫描血糖和指血血糖强相关(r=0.87,P=0.000),扫描血糖的总体MARD为14.28±13.40%,Parker’s误差分析结果显示99.3%的数据均落在A区和B区。探头佩戴第一天的MARD与第2~14天的MARD分别为16.55%和14.35%,但尚未达到统计学差异(t=1.232,P=0.218)。日内最大血糖波动幅度(LAGE)<5.8mmol/L时,MARD与血糖浓度无关;LAGE>5.8mmol/L时,MARD与血糖浓度负相关。结论瞬感扫描式动态血糖监测系统在藏汉两族2型糖尿病患者中的应用准确性良好。其MARD主要受患者血糖波动和血糖浓度的影响,当血糖波动大时,瞬感扫描式动态血糖监测结果在极低血糖范围的偏差最大。
Objective This study aimed to evaluate the accuracy of the flash glucose monitor freestyle libre system in Chinese Tibet and Han population with type 2 diabetes.Methods A total of 68 Tibet and Han subjects hospitalized in department of Endocrinology and metabolism from august 2017 to December 2017 with type 2 diabetes were underwent up to 14 days continuous glucose monitoring with the flash glucose monitoring system(Freestyle libre).During these 14 days,all the patients were measured fasting glucose and 2 h glucose after three meals with capillary blood by enzyme electrode method(Glucose/Lactate analyzer)and simultaneously recorded Freestyle Libre results(Scan glucose).The accuracy of Freestyle libre was evaluated by the capillary glucose reference.And the infecting factors of MARD of freestyle libre system were analyzed.Results The scan glucose results were positive correlation with capillary glucose results(r=0.87,P=0.000).The overall MARD of Freestyle Libre system was 14.28±13.40%.The percentage of results in Zone A and B of Parker’s error grid were 99.3%.The MARD of the first day and days 2-14 were 16.55%and 14.35%respectively,but there were no significant difference(t=1.232,P=0.218).Multiple stepwise regression analysis showed that MARD had no association with glucose level when LAGE<5.8 mmol/L,but negative association with glucose level when LAGE≥5.8 mmol/L.Conclusion The Freestyle Libre system works well for Chinese Tibet and Han population with type 2 diabetes,and the MARD was mainly influenced by glucose level and glucose fluctuation.The bias of scan glucose of Freestyle Libre system was highest in extremely low blood glucose level when there was a larger range of blood glucose excusion.
作者
龙文春
王溯源
邬云红
姚璿羽
张惠勤
景桂琼
刘娜
李雪雪
万冬梅
范吴义
黄伦浪
唐冬梅
叶燕
王曦
李明霞
张成慧
张丹
孙舒瑶
孙曾梅
Long Wenchun;Wang Suyuan;Wu Yunhong;Yao Xuanyu;Zhang Huiqing;Jing Guiqiong;Liu Na;Li Xuexue;Wan Dongmei;Fang Wuyi;Huang Lunlang;Tang Dongmei;Ye Yan;Wang Xi;Li Mingxia;Zhang Chenghui;Zhang Dan;Sun Shuyao;Sun Zengmei(Department of Endocrinology,Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region,Chengdu 610041,China)
出处
《四川解剖学杂志》
2020年第4期1-4,共4页
Sichuan Journal of Anatomy
基金
四川省卫生和计划生育科研课题(17PJ069)
作者简介
通讯作者:孙曾梅(1982-),女,四川省内江市人,硕士,主管护师,研究方向:护理与血糖监测,E-mail:519795319@qq.com。
