摘要
目的:观察红藤汤加减联合盐酸莫西沙星治疗妇科急性盆腔炎的疗效及对血清炎性指标的影响。方法:选取2019年5月~2020年5月在我院诊治的急性盆腔炎患者90例,采用随机数字法分为对照组(45例)和观察组(45例),观察组患者给予红藤汤加减联合盐酸莫西沙星,对照组患者给予盐酸莫西沙星,比较两组患者的临床治疗效果及治疗期间不良反应发生率并比较治疗前后血清炎性指标降钙素原(procalcitonin,PCT)、白介素-1β(interleukin-1β,IL-1β)及C反应蛋白(C-reactive protein,CRP)水平及血液流变学指标。结果:观察组患者临床治疗总有效率为41例(91.11%),对照组患者临床治疗总有效率为34例(75.56%),差异具有统计学意义(P<0.05);治疗前,两组患者的血清PCT、IL-1β及CRP及血液流变学相比,差异无统计学意义(P>0.05);经治疗后,与对照组相比,观察组患者的血清PCT、IL-1β、CRP水平、血浆粘度、低切血粘度及高切血粘度均显著降低,差异具有统计学意义(P<0.05);两组患者治疗期间不良反应发生率比较,差异无统计学意义(P>0.05)。结论:红藤汤加减联合盐酸莫西沙星治疗妇科急性盆腔炎的临床效果较好、安全性较高,能够显著降低血清炎性指标水平。
Objective:To investigate the effect of using Modified Hongteng Decoction combined with Moxifloxacin Hydrochloride in the treatment of gynecological acute pelvic inflammatory disease and its influnce on serum inflammatory markers.Methods:90 cases of patients with acute pelvic inflammatory disease were collected from May 2019 to May 2020 in our hospital diagnosis and treatment,according to the random number method divided into a controlled group(45 cases)and an observation group(45 cases),the observation group patients were given Modified Hongteng Decoction combined with Moxifloxacin Hydrochloride,the controlled group patients were given Moxifloxacin Hydrochloride,compared with the clinical treatment effect and incidence of adverse reactions during treatment of the two groups and compared the serum inflammatory indicators before and after treatment suas as PCT,IL-1β,CRP and hemodynamic index.Results:The total effective rate of clinical treatment in the observation group was 41 cases(91.11%)and 34 cases(75.56%)in the controlled group,the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in serum PCT,IL-1βand CRP between the two groups(P>0.05).After treatment,compared with the controlled group,the level of serum PCT,IL-1β,CRP and plasma viscosity,low and high viscosity of cut blood in the observation group were significantly decreased,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups during treatment(P>0.05).Conclusion:Modified Hongteng Decoction combined with Moxifloxacin Hydrochloride in the treatment of gynecological acute pelvic inflammatory diseasehas good clinical effect and high safety,and can significantly reduce the level of serum inflammatory indicators.
作者
周强
龚红霞
曹莉莉
赵欣
何鹏
ZHOU Qiang;GONG Hongxia;CAO Lili;ZHAO Xin(Department of Obstetrics and Gynecology,Putuo Maternal and Child Health Care Hospital of Shanghai,Shanghai 200062,China)
出处
《四川中医》
2022年第8期155-157,共3页
Journal of Sichuan of Traditional Chinese Medicine
基金
上海市医药卫生科研面上项目(编号:2016-239)
关键词
急性盆腔炎
红藤汤
盐酸莫西沙星
炎性指标
Acute pelvic inflammatory disease
Hongteng Decoction
Moxifloxacin Hydrochloride
Inflammatory markers
作者简介
第一作者:周强,本科,副主任医师,研究方向:妇产疾病,E-mail:shixs8855@163.com;通讯作者:赵欣,本科,主任医师,研究方向:妇产疾病,E-mail:Kenny-zhao@163.com。
