摘要
目的:探讨《女科证治准绳》中调经方的用药规律及王肯堂论治月经病学术特色。方法:收集《女科证治准绳》“调经门”中经候总论、经闭、血崩里所包含的中药复方,对药物组成进行数据整理及规范化处理,录入Microsoft Excel建立相应数据库,应用SPSS构建关联规则和聚类分析,后采用Gephi对药物进行复杂网络分析,从而得出复方中的高频药物及配伍规律。结果:中药复方164首中涉及中药共计208味,通过筛选药物出现频次得到24味中药,形成4个聚类。高频中药(出现频次≥20次)为当归、川芎、白芍等15味。结论:《女科证治准绳》中调经方组成多以补虚药、甘温药为主,聚类分析及核心药物组成均涉及四物汤中的组成药物,体现了王肯堂在月经病治疗中以善用四物汤为主方化裁、调经首要辨色、首选甘温补虚的用药特点。
Objective:To explore the medication regularity of prescriptions to regulate menstruation in Female Science Certification Criteria and WANG Kentang’s academic characteristics of treating menstrual diseases.Methods:Collecting the Chinese herbal compounds contained in Tiaojing Chapter in Female Science Certification Criteria,organizes data and standardize the composition of the medicine,enter data into Microsoft Excel,establishes a corresponding database,construct the association rules and the cluster analysis with SPSS,builds a complex network by Gephi application,analyzes the occurrence and compatibility of high frequency.Results:There are 208 Chinese herbal medicines in the 164 Chinese herbal compounds,we get 24 medicines and form 4 clusters;15 high-frequency Chinese medicines(Frequency≥20 times)are radix angelica sinensis,ligusticum wallichii,radices paeoniae alba,etc.Conclusion:The medicines of prescriptions to regulate menstruation rely mainly on tonic drug,warm and sweet flavor medicine.Cluster analysis and core drug composition all involve the constituent drugs in Siwu Decoction,which reflects the characteristics of WANG Kentang’s good use of Siwu Decoction,adjusting the primary color,and the first choice of sweet temperature and deficiency in the treatment of menstrual disease.
作者
冯浩妍
杨雅琪
万幸
李莉
FENG Haoyan;YANG Yaqi;WANG Xin(The First Clinical School of Medicine,Guangzhou University of Traditional Chinese Medicine,Guangzhou Guangdong 510000,China)
出处
《四川中医》
2022年第10期21-25,共5页
Journal of Sichuan of Traditional Chinese Medicine
基金
广东省中医药局科研项目(编号:20202066)
关键词
女科证治准绳
数据挖掘
调经方
用药规律
Female Science Certification Criteria
Data mining
Prescriptions to regulate menstruation
Medication regularity