摘要
目的分析出血性中风恢复期中医临床用药,为出血性中风恢复期临床提供思路及方法。方法检索时间为建库-2021年10月,发表在中英文数据库的文献。提取文献中出血性中风恢复期处方用药的规律,并运用频数统计、聚类分析及关联规则分析潜在的治疗方法。结果共整理出103个方剂,134味药。结果显示出血性中风恢复期处方频率依次为补阳还五汤、通瘀汤、破瘀醒神汤、天麻钩藤饮、通窍活络汤、半夏白术天麻汤、地黄饮子、养血清脑颗粒、益气活血散、中风II号口服液、逐痰通络汤。出血性中风恢复期用药频次≥10次的药物依次为当归、黄芪、桃仁、红花、川芎、赤芍、地龙、丹参、水蛭、全蝎、牛膝、石菖蒲、石斛、大黄、延胡索、羌活、三七、胆南星、天麻、熟地黄、郁金、鸡血藤、白芍。结论补益气血为出血性中风恢复期的根本治法。活血化瘀是出血性中风恢复期的核心治疗手段。熄风化痰是出血性中风恢复期治疗的重要组成部分。
Objective To analyze the clinical medication of traditional Chinese medicine in the recovery period of hemorrhagic stroke,and to provide ideas and methods for the clinical treatment of hemorrhagic stroke in the recovery period.Methods The retrieval time was from the establishment of the database to October 2021.The law of prescription medication in the recovery period of hemorrhagic stroke was extracted from the literature,and the potential treatment methods were analyzed by frequency statistics,cluster analysis and association rules.Results A total of 103 prescriptions and 134 medicines were sorted out.The results showed that the prescription frequency in the recovery period of hemorrhagic stroke was Buyang Huanwu Decoction,Tongyu decoction,poyu Xingshen decoction,Tianma Gouteng Decoction,Tongqiao Huoluo decoction,Banxia Baizhu Tianma decoction,Dihuang Yinzi,Yangxue Qingnao Granule,Yiqi Huoxue powder,apoplexy II oral liquid and Zhutan Tongluo decoction.The drugs with medication frequency≥10 times in the recovery period of hemorrhagic stroke were Angelica sinensis,Astragalus membranaceus,peach kernel,safflower,Ligusticum chuanxiong,red peony,earthworm,Salvia miltiorrhiza,leech,scorpion,Achyranthes bidentata,gladiolus,Dendrobium,rhubarb,corydalis Corydalis,notopterygium,Panax notoginseng,dannanxing,Gastrodia elata,radix rehmanniae,turmeric,Caulis Spatholobi and Radix Paeoniae Alba.Conclusion Supplementing Qi and blood is the fundamental treatment for hemorrhagic stroke in the recovery period.Promoting blood circulation and removing blood stasis is the core treatment of hemorrhagic stroke in the recovery period.Calming wind and resolving phlegm is an important part of the recovery treatment of hemorrhagic stroke.
作者
吴雷
张艺缤
张冬梅
常天瀛
张影
徐寒莹
吴桐
王健
兰天野
Wu Lei;Zhang Yibin;Zhang Dongmei;Chang Tianyin;Zhang Ying;Xu Hanying;Wu Tong;Wang Jian;Lan Tianye(College of Traditional Chinese Medicine,Changchun University of Chinese Medicine,Changchun 130117,China;The Affiliated Hospital to Changchun University of Traditional Chinese Medicine,Changchun 130021,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2023年第3期974-983,共10页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家科学技术部国家重点研发计划“中医药现代化研究”专项(2018YFC1705003):急性出血性中风病证结合通治方案的临床评价研究,负责人:廖晓凌
国家科学技术部国家重点研发计划项目“中医药现代化研究”专项(2019YFC1709902):基于“证候要素”中风病健康状态辨识与干预研究,负责人:王健
吉林省临床医学研究中心吉林省科技发展计划项目(20190905005SF):吉林省中医脑病临床医学研究中心项目科研任务,负责人:王健
关键词
出血性中风
恢复期
数据挖掘
中医药
Hemorrhagic stroke
Recovery period
Data mining
Traditional Chinese medicine
作者简介
通讯作者:王健,主任医师,博士生导师,主要研究方向:中医内科学脑病方向的研究;通讯作者:兰天野,主任医师,硕士生导师,主要研究方向:中医内科学脑病方向的研究
