摘要
目的探讨老年反复上呼吸道感染患者采用基于肾虚邪伏理论的温肾祛邪法治疗效果,分析其对患者免疫功能的影响。方法选取2018-09-01-2020-09-01河南省荣军医院收治的125例老年反复上呼吸道感染患者作为研究对象,抽签法将其分为2组,对照组62例接受抗感染及对症治疗,观察组63例加用基于肾虚邪伏理论的温肾祛邪法治疗,比较2组患者免疫功能、感染发作情况以及不良反应等。结果治疗后,观察组发病次数为(3.15±0.30)次,低于对照组的(4.69±0.52)次,t=20.321,P<0.05;发病持续时间为(4.07±0.53)d,低于对照组的(6.44±0.91)d,t=17.827,P<0.05;发病间隔时间为(3.95±0.69)个月,高于对照组的(2.51±0.43)个月,t=13.977,P<0.05。观察组NK细胞为(17.88±1.83)%,高于对照组的(15.70±1.62)%,t=7.048,P<0.05;CD4;/CD8;为(1.59±0.36),高于对照组的(1.47±0.20),t=2.299,P<0.05。观察组头痛汗出积分为(2.20±0.21)分,低于对照组的(3.31±0.52)分,t=15.693,P<0.05;咳嗽咽痛积分为(2.05±0.25)分,低于对照组的(3.17±0.48)分,t=16.398,P<0.05;形寒肢冷积分为(1.86±0.20)分,低于对照组的(2.70±0.35)分,t=16.507,P<0.05;腰膝酸软积分为(1.93±0.24)分,低于对照组的(2.86±0.42)分,t=15.230,P<0.05。结论以温肾祛邪法为治疗原则组成的桂附益卫汤能缓解老年反复上呼吸道感染患者头痛汗出、咳嗽咽痛等症状,降低发病频率,改善患者免疫功能,效果优于西药。
Objective To investigate the therapeutic effect of the method of warming the kidney and eliminating pathogens based on the theory of kidney deficiency and evil in elderly patients with recurrent upper respiratory tract infection,and analyze its influence on the immune function of the patients.Methods Totally 125 elderly patients with recurrent upper respiratory tract infections in our hospital from September 1,2018 to September 1,2020 were included as research objects.They were divided into 2 groups by lottery.62 cases in the control group received anti-infection and symptomatic treatment,and 63 cases in the observation group adopted the method of warming the kidney and eliminating pathogens.In addition,the therapy based on the theory of kidney deficiency and evil vulnerabilities was used to compare the immune function,the onset of infection and adverse reactions between the two groups of patients.Results After treatment,the number of onsets in the observation group was(3.15±0.30)times,which was lower than(4.69±0.52)times in the control group(t=20.321,P<0.05).The duration of onset in the observation group was(4.07±0.53)d,which was lower than that of the control group(6.44±0.91)d,t=17.827,P<0.05.The interval between onsets in the observation group was(3.95±0.69)months,which was higher than(2.51±0.43)months in the control group(t=13.977,P<0.05).The NK cells in the observation group were(17.88±1.83)%,which was higher than(15.70±1.62)%in the control group(t=7.048,P<0.05).The CD4;/CD8;of the observation group was(1.59±0.36)higher than that of the control group(1.47±0.20),t=2.299,P<0.05.The score of headaches and sweating in the observation group was(2.20±0.21)lower than that of the control group(3.31±0.52)points,t=15.693,P<0.05.The score of cough and sore throat in the observation group was(2.05±0.25)points lower than that of the control group(3.17±0.48)points(t=16.398,P<0.05).The cold limb score of the observation group was(1.86±0.20)points lower than that of the control group(2.70±0.35)points(t=16.507,P<0.05).The waist and knee soreness score of the observation group was(1.93±0.24)points lower than that of the control group(2.86±0.42)points(t=15.230,P<0.05).Conclusion The guifu yiwei decoction,which is based on the principle of warming the kidney and eliminating evils,can significantly relieve the symptoms of headache,sweating,cough and sore throat in elderly patients with repeated upper respiratory tract infections,reduce the frequency of disease,and improve the immune function of patients.The effect is better than western medicine.
作者
赵学娟
孙岚英
王志刚
ZHAO Xue-juan;SUN Lan-ying;WANG Zhi-gang(Rongjun Hospital of Henan Province,Xinxiang 450003,China)
出处
《社区医学杂志》
CAS
2022年第5期281-284,共4页
Journal Of Community Medicine
关键词
肾虚邪伏理论
温肾祛邪法
老年反复上呼吸道感染
免疫功能
theory of kidney deficiency
warming kidney and eliminating evils
recurrent upper respiratory tract infection in the elderly
immune function
作者简介
通信作者:赵学娟,女,河南新乡人,硕士,主治医师,主要从事急慢性呼吸道疾病相关的临床研究工作。E-mail:hnzhaoxuejuan@163.com
