摘要
目的探究不同过敏风险儿童的血清维生素A、D水平,为高风险过敏儿童提供合理补充维生素A、D的科学依据。方法选取2017-03-01-2019-03-01泰安市中心医院保健护理的6个月龄婴儿1000名,依据《婴儿过敏风险评估表》评分,分为过敏高风险组597名、中风险组318名、低风险组85名,通过检测婴儿的末梢血维生素A、D的水平,利用方差分析和χ^(2)检验比较3组不同风险婴儿维生素A、D水平之间的差异。结果低过敏风险组婴儿维生素A水平(0.26±0.05)mg/L高于中(0.19±0.04)mg/L、高过敏风险(0.20±0.04)mg/L 2组婴儿,差异有统计学意义,均P<0.001;中(64.5%,205/318)、高(80.7%,482/597)风险2组婴儿维生素A水平均处于维生素A缺乏高风险状态,低过敏风险组婴儿维生素A水平处于亚临床缺乏风险状态(41.2%,35/85)。低(29.33±5.73)ng/mL、中(17.81±3.75)ng/mL、高(14.89±3.71)ng/mL 3组不同过敏风险婴儿维生素D水平存在差异,差异有统计学意义,均P<0.001;中(36.2%,115/318)、高过敏风险(62.8%,375/597)2组婴儿维生素D水平处于维生素D不足状态,低过敏风险组婴儿维生素D水平适宜(20.0%,17/85)。结论过敏风险较高的婴儿常规补充维生素A、D后体内水平仍然处于缺乏或不足状态,因此,这部分儿童维生素A、D的补充应更积极,在常规补充的基础上,需适当加大剂量,以预防其缺乏。
Objective To explore the serum vitamin A and vitamin D levels of infants at different risk of allergies,and provide a scientific basis for reasonable vitamin A and D supplementation for infants with high-risk allergies.Methods A total of 1,0006-month-old infants from 2017-03-01 to 2019-09-01 were selected from Tai’an Central Hospital.According to the score of"Infant Allergy Risk Assessment Table",they were divided into 597 cases in the high-risk group of allergies,318 cases in the medium-risk group,and 85 cases in the low-risk group.The differences between vitamin A and vitamin D levels in infants at different risks were compared using analysis of variance andχ^(2)test by measuring the levels of vitamin A and vitamin D in infants’peripheral blood.Results The vitamin A level(0.26±0.05)mg/L of infants in the low-risk group was higher than that of the medium(0.19±0.04)mg/L and high allergy risk(0.20±0.04)mg/L,and the difference was statistically significant(P<0.001);The two groups of infants at medium(64.5%,205/318)and high(80.7%,482/597)allergic risks were at high risk of vitamin A deficiency,but the hypoallergenic risk group was at risk of subclinical deficiency(41.2%,35/85).There were differences in vitamin D levels in infants at different risk of allergies in the low(29.33±5.73)ng/ml,medium(17.81±3.75)ng/ml,and high(14.89±3.71)ng/mL,and the differences was statistically significant(P<0.001);The vitamin D levels of infants in the middle(36.2%,115/318)and high allergy risk(62.8%,375/597)groups were in a state of vitamin D deficiency,and the vitamin D levels of infants in the low allergic risk group were appropriate(20.0%,17/85).Conclusions Infants at higher risk of allergies are still in a state of deficiency after routine vitamin A and D supplementation.Therefore,the supplementation of vitamin A and D in these infants should be more active and increase the dose appropriately on the basis of conventional supplement to prevent vitamin A and D deficiency.
作者
陈晓云
冯琳琳
齐云云
孟婷婷
孙丰燕
CHEN Xiao-yun;FENG Lin-lin;QI Yun-yun;MENG Ting-ting;SUN Feng-yan(Department of Pediatrics,The Affiliated Taian City Central Hospital of Qingdao University,Taian 271000,China)
出处
《社区医学杂志》
CAS
2022年第22期1285-1289,共5页
Journal Of Community Medicine
作者简介
通信作者:陈晓云,女,山东泰安人,博士,主任医师,主要从事儿童内分泌的研究工作。E-mail:cxyp1206@163.com
