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金振口服液联合阿奇霉素治疗儿童肺炎支原体肺炎(非重症)的临床疗效

Clinical Effect of Jinzhen Oral Liquid Combined with Azithromycin in Treating Children with Mycoplasma Pneumoniae Pneumonia(Non-severe)
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摘要 目的:观察金振口服液联合阿奇霉素治疗儿童肺炎支原体肺炎(MPP)(非重症)的临床疗效。方法:选取阳江市人民医院2019年1月至2021年1月收治的168例确诊儿童MPP(非重症)患儿,按入组顺序随机分为观察组和对照组,每组84例。观察组使用金振口服液联合阿奇霉素治疗,对照组单纯使用阿奇霉素治疗,比较两组患儿的临床效果(退热时间、咳嗽时间)、治疗前后血清炎症指标[白细胞介素(IL)-2、IL-6、超敏C反应蛋白(hs-CRP)]水平。结果:观察组患儿总有效率高于对照组,差异具有统计学意义(P<0.05);治疗后,观察组患儿血清IL-2、IL-6、hs-CRP水平低于对照组,差异具有统计学意义(P<0.05)。结论:金振口服液联合阿奇霉素治疗MPP患儿,可更好地缓解患儿症状,减轻炎症反应。 Objective To observe the clinical effect of Jinzhen oral liquid combined with azithromycin in the treatment of children with mycoplasma pneumoniae pneumonia(MPP)(non-severe).Methods A total of 168 children diagnosed with MPP(non-severe)admitted to Yangjiang People's Hospital from January 2019 to January 2021 were randomly divided into an observation group and a control group according to the order of admission,84 cases in each group.The observation group was treated with Jinzhen oral liquid combined with azithromycin,and the control group was treated with azithromycin.The clinical effects(the time of fever reduction and cough),serum inflammation indexes[Interleukin(IL)-2,IL-6 and hypersensitive C-reactive protein(HS-CRP)]before and after treatment were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).After treatment,the serum levels of IL-2,IL-6 and hs-CRP in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Jinzhen oral liquid combined with azithromycin in the treatment of MPP children,can better relieve the symptoms of children,reduce inflammation.
作者 戴本启 张志梅 陈捷 罗玉婷 麦月嫦 DAI Benqi;ZHANG Zhimei;CHEN Jie;LUO Yuting;Mai Yuechang(Yangjiang People's Hospital,Guangdong Yangjiang 529500)
机构地区 阳江市人民医院
出处 《深圳中西医结合杂志》 2023年第17期39-41,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词 肺炎支原体肺炎 金振口服液 阿奇霉素 儿童 Mycoplasma pneumoniae pneumonia Jinzhen oral liquid Azithromycin Children
作者简介 戴本启,男,副主任医师,主要研究方向是小儿内科呼吸。
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