摘要
目的分析贫血与儿童社区获得性肺炎(CAP)疾病严重程度的关系。方法选取2018年6月至2021年12月本院收治的CAP患儿为研究对象,依据CAP患儿疾病严重程度,分为重度CAP组(n=48)和轻度CAP组(n=154)。比较组间一般资料、临床体征和症状、实验室指标差异,分析贫血与儿童CAP疾病严重程度的相关性。结果单因素分析结果显示,呼吸困难、中性粒细胞、淋巴细胞、血红蛋白(HB)、凝血酶原时间、D-二聚体、C反应蛋白(CRP)、降钙素原、红细胞沉降率(ESR)、乳酸脱氢酶(LDH)、谷草转氨酶(AST)、尿素氮(BUN)组间比较具有统计学差异(P均<0.05)。二元Logistic回归分析结果显示,贫血、D-二聚体、CRP、LDH是儿童CAP重度病情的独立危险因素(P均<0.01)。Pearson相关分析结果显示,HB与D-二聚体、CRP、LDH均呈显著负相关(P均<0.01)。结论贫血是儿童CAP疾病严重程度的危险因素,在临床中应注意对其的监测和管理。
Objective To analyze the relationship between anemia and the severity of community-acquired pneumonia(CAP)in children.Methods Children with cap admitted to our hospital from June 2018 to December 2021 were selected as the research objects.According to the severity of the disease,they were divided into severe CAP group(n=48)and mild CAP group(n=154).The differences of general data,clinical signs and symptoms,and laboratory indicators between groups were compared,and the correlation between anemia and the severity of cap disease in children was analyzed.Results univariate analysis showed that there were significant differences in dyspnea,neutrophils,lymphocytes,hemoglobin(HB),prothrombin time,D-dimer,C-reactive protein(CRP),procalcitonin,erythrocyte sedimentation rate(ESR),lactate dehydrogenase(LDH),aspartate aminotransferase(AST),urea nitrogen(BUN)among the groups(P<0.05).The results of binary logistic regression analysis showed that anemia,D-dimer,CRP and LDH were independent risk factors for severe CAP in children(P<0.01).Pearson correlation analysis showed that Hb was significantly negatively correlated with D-dimer,CRP and LDH(all P<0.01).Conclusion Anemia is a risk factor for the severity of cap disease in children,and its monitoring and management should be paid attention to in clinical practice.
作者
刘玮
罗中凯
LIU Wei;LUO Zhong-kai(Lu’an civily hospital,Pediatrics,Anhui Lu'an 237000,China)
出处
《中国实验诊断学》
2023年第2期145-148,共4页
Chinese Journal of Laboratory Diagnosis
基金
安徽省科技支撑计划项目(编号:2020039422-04)
关键词
贫血
肺炎
儿童
相关性
anemia
Pneumonia
Children
relevance
作者简介
通讯作者:罗中凯
