Ten N (4 substituted pyrimidin 2 yl) 2 trifluoroacetylamino benzenesulfonylureas were synthesized. Their structures were confirmed by elemental analysis and 1H NMR. Some of the compounds showed good herbicidal act...Ten N (4 substituted pyrimidin 2 yl) 2 trifluoroacetylamino benzenesulfonylureas were synthesized. Their structures were confirmed by elemental analysis and 1H NMR. Some of the compounds showed good herbicidal activity.展开更多
The complexes of zinc chloride and zinc nitrate with 2 amino 4,6 dimethyl pyrimidine (ADMP) were prepared through reflux in alcohol. The compositions of the complexes Zn(ADMP)2Cl2 (b) and Zn(ADMP)2(NO3)2·4H2O (c)...The complexes of zinc chloride and zinc nitrate with 2 amino 4,6 dimethyl pyrimidine (ADMP) were prepared through reflux in alcohol. The compositions of the complexes Zn(ADMP)2Cl2 (b) and Zn(ADMP)2(NO3)2·4H2O (c) were determined by chemical and elemental analyses. The complexes were characterized by IR, XPS, 1H NMR and TG DTG techniques. The constant volume combustion energies of ADMP and the complexes, ΔcE, were determined by a precise rotating bomb calorimeter at 298.15K. They were (-3664.53±1.18)kJ·mol-1, (-7130.94±3.69)kJ·mol-1, and (-7637.87±5.71)kJ·mol-1. Their standard enthalpies of combustion,, and standard enthalpies of formation, , were calculated. They were (-3666.39±1.18)kJ·mol-1, (-7129.70±3.69)kJ·mol-1, (-7632.91 ±5.71)kJ·mol-1 and (19.09±1.43)kJ·mol-1, (-411.96±4.03)kJ·mol-1, (-1153.28±6.02)kJ·mol-1.展开更多
以硫脲和氯乙酸为原料,在无溶剂和350 W微波辐射4 m in条件下,缩合生成中间体2,4-噻唑烷二酮(Ⅰ)产率91.5%;随后在无溶剂和400 W微波辐射5 m in条件下,通过V ilsm e ier甲酰化反应,生成中间体4-氯-5-甲酰基噻唑-2(3H)-酮(Ⅱ),产率86.7%...以硫脲和氯乙酸为原料,在无溶剂和350 W微波辐射4 m in条件下,缩合生成中间体2,4-噻唑烷二酮(Ⅰ)产率91.5%;随后在无溶剂和400 W微波辐射5 m in条件下,通过V ilsm e ier甲酰化反应,生成中间体4-氯-5-甲酰基噻唑-2(3H)-酮(Ⅱ),产率86.7%;最后以正丙醇为溶剂,450 W微波辐射7 m in条件下,成环得到5-氨基-噻唑[4,5-d]嘧啶-2(3H)-酮(Ⅲ),产率80.5%。反应总产率为63.9%。合成产物与中间体的结构经1HNMR,MS和元素分析确认。展开更多
The title compound 3 was synthesized from diethylguanidine nitrate（2） obtained from diethylamine, CaCN2 and HNO3. The mixture consisted of 0.5 mol 2, 0.55 mol acetonyl propionate, 3 g benzyltriethylammonium chloride...The title compound 3 was synthesized from diethylguanidine nitrate（2） obtained from diethylamine, CaCN2 and HNO3. The mixture consisted of 0.5 mol 2, 0.55 mol acetonyl propionate, 3 g benzyltriethylammonium chloride, and 44 g NaOH was refluxed for 4 hours to give 85 g 3, in yield 94.6%.展开更多
The Cu（Ⅱ）complexes of 2-aminopyrimidine were synthesized and characterized by elemental analyses,TG-DTG.The dissolution enthalpies of the[AP（s）+CuCl2·2H2O（s）]and Cu（AP） Cl2（s）in 100.00 mL 2 mol.L-1HCl ...The Cu（Ⅱ）complexes of 2-aminopyrimidine were synthesized and characterized by elemental analyses,TG-DTG.The dissolution enthalpies of the[AP（s）+CuCl2·2H2O（s）]and Cu（AP） Cl2（s）in 100.00 mL 2 mol.L-1HCl solution were measured at 298.15 K by classical solution calorimetry.The standard molar reaction enthalpy of the coondination reaction of 2-aminopyrimidine with Cu（Ⅱ）has been determined by a thermochemical cycle(ΔrH<sup>○-m=-1.92±0.27kJ·mol-1).From the result,the standard molar enthalpy of formation ΔfH<sup>○-m[Cu（AP）Cl2,s,298.15K] of Cu（AP）Cl2 has been calculated to be-297.46±1.72kJ·mol-1.展开更多
Synthesis steps of 4,5 diamino 6 hydroxy 2 mercaptopyrimidine were improved on cyclocondensation of ethyl cyanoacetate with thiourea,nitrosation and reduction to obtain the product in 89% yield with high purity on ind...Synthesis steps of 4,5 diamino 6 hydroxy 2 mercaptopyrimidine were improved on cyclocondensation of ethyl cyanoacetate with thiourea,nitrosation and reduction to obtain the product in 89% yield with high purity on industrial scale.展开更多
文摘Ten N (4 substituted pyrimidin 2 yl) 2 trifluoroacetylamino benzenesulfonylureas were synthesized. Their structures were confirmed by elemental analysis and 1H NMR. Some of the compounds showed good herbicidal activity.
文摘The complexes of zinc chloride and zinc nitrate with 2 amino 4,6 dimethyl pyrimidine (ADMP) were prepared through reflux in alcohol. The compositions of the complexes Zn(ADMP)2Cl2 (b) and Zn(ADMP)2(NO3)2·4H2O (c) were determined by chemical and elemental analyses. The complexes were characterized by IR, XPS, 1H NMR and TG DTG techniques. The constant volume combustion energies of ADMP and the complexes, ΔcE, were determined by a precise rotating bomb calorimeter at 298.15K. They were (-3664.53±1.18)kJ·mol-1, (-7130.94±3.69)kJ·mol-1, and (-7637.87±5.71)kJ·mol-1. Their standard enthalpies of combustion,, and standard enthalpies of formation, , were calculated. They were (-3666.39±1.18)kJ·mol-1, (-7129.70±3.69)kJ·mol-1, (-7632.91 ±5.71)kJ·mol-1 and (19.09±1.43)kJ·mol-1, (-411.96±4.03)kJ·mol-1, (-1153.28±6.02)kJ·mol-1.
文摘以硫脲和氯乙酸为原料,在无溶剂和350 W微波辐射4 m in条件下,缩合生成中间体2,4-噻唑烷二酮(Ⅰ)产率91.5%;随后在无溶剂和400 W微波辐射5 m in条件下,通过V ilsm e ier甲酰化反应,生成中间体4-氯-5-甲酰基噻唑-2(3H)-酮(Ⅱ),产率86.7%;最后以正丙醇为溶剂,450 W微波辐射7 m in条件下,成环得到5-氨基-噻唑[4,5-d]嘧啶-2(3H)-酮(Ⅲ),产率80.5%。反应总产率为63.9%。合成产物与中间体的结构经1HNMR,MS和元素分析确认。
文摘The title compound 3 was synthesized from diethylguanidine nitrate（2） obtained from diethylamine, CaCN2 and HNO3. The mixture consisted of 0.5 mol 2, 0.55 mol acetonyl propionate, 3 g benzyltriethylammonium chloride, and 44 g NaOH was refluxed for 4 hours to give 85 g 3, in yield 94.6%.
文摘The Cu（Ⅱ）complexes of 2-aminopyrimidine were synthesized and characterized by elemental analyses,TG-DTG.The dissolution enthalpies of the[AP（s）+CuCl2·2H2O（s）]and Cu（AP） Cl2（s）in 100.00 mL 2 mol.L-1HCl solution were measured at 298.15 K by classical solution calorimetry.The standard molar reaction enthalpy of the coondination reaction of 2-aminopyrimidine with Cu（Ⅱ）has been determined by a thermochemical cycle(ΔrH<sup>○-m=-1.92±0.27kJ·mol-1).From the result,the standard molar enthalpy of formation ΔfH<sup>○-m[Cu（AP）Cl2,s,298.15K] of Cu（AP）Cl2 has been calculated to be-297.46±1.72kJ·mol-1.
文摘Synthesis steps of 4,5 diamino 6 hydroxy 2 mercaptopyrimidine were improved on cyclocondensation of ethyl cyanoacetate with thiourea,nitrosation and reduction to obtain the product in 89% yield with high purity on industrial scale.
