β-Sialon/ZrN bonded corundum composites were synthesized using fused white corundum,alumina micro powder,zircon and carbon black by nitridation reaction sintering process. Phase composition and microstructure of the ...β-Sialon/ZrN bonded corundum composites were synthesized using fused white corundum,alumina micro powder,zircon and carbon black by nitridation reaction sintering process. Phase composition and microstructure of the synthesized composites were investigated by X-ray powder diffraction and scanning electronic microscope,and the formation process of the composites was discussed. The results show that the composites with different compositions can be obtained by controlling the heating temperature and contents of zircon and carbon black. The proper temperature to synthesize the composites is 1773 K.展开更多
化疗作为癌症治疗的重要手段,在肿瘤治疗领域扮演着关键角色。然而,化疗相关腹泻是令人困扰的不良反应,可导致化疗剂量降低、治疗延迟或中止、治疗方案改变,严重时可危及生命。5-氟尿嘧啶和伊立替康是导致化疗相关腹泻最常见的化疗药物...化疗作为癌症治疗的重要手段,在肿瘤治疗领域扮演着关键角色。然而,化疗相关腹泻是令人困扰的不良反应,可导致化疗剂量降低、治疗延迟或中止、治疗方案改变,严重时可危及生命。5-氟尿嘧啶和伊立替康是导致化疗相关腹泻最常见的化疗药物,近年来随着三药联合化疗方案运用的增加,腹泻相关死亡病例也随之增加,这可能与中性粒细胞减少性小肠结肠炎有关。洛哌丁胺是治疗化疗相关腹泻的主要药物,但如何管理洛哌丁胺治疗无效的腹泻是临床最关注的问题。因此,本专家组基于国内外循证医学证据,结合临床实践经验,对化疗相关腹泻的定义、发病机制、分类、评估、诊断、干预和预防进行充分的评估与讨论,最终形成《化疗相关腹泻全程管理中国专家共识(2025年版)》,以便进一步规范对化疗相关腹泻的全程管理。本共识已在国际实践指南注册与透明化平台(Practice guideline REgistration for transPAREncy,PREPARE)上注册,注册编号为PREPARE-2024CN1246。展开更多
基金Project(50274021) supported by the National Natural Science Foundation of China and Baoshan Iron and Steel Co., Ltd.
文摘β-Sialon/ZrN bonded corundum composites were synthesized using fused white corundum,alumina micro powder,zircon and carbon black by nitridation reaction sintering process. Phase composition and microstructure of the synthesized composites were investigated by X-ray powder diffraction and scanning electronic microscope,and the formation process of the composites was discussed. The results show that the composites with different compositions can be obtained by controlling the heating temperature and contents of zircon and carbon black. The proper temperature to synthesize the composites is 1773 K.
文摘化疗作为癌症治疗的重要手段,在肿瘤治疗领域扮演着关键角色。然而,化疗相关腹泻是令人困扰的不良反应,可导致化疗剂量降低、治疗延迟或中止、治疗方案改变,严重时可危及生命。5-氟尿嘧啶和伊立替康是导致化疗相关腹泻最常见的化疗药物,近年来随着三药联合化疗方案运用的增加,腹泻相关死亡病例也随之增加,这可能与中性粒细胞减少性小肠结肠炎有关。洛哌丁胺是治疗化疗相关腹泻的主要药物,但如何管理洛哌丁胺治疗无效的腹泻是临床最关注的问题。因此,本专家组基于国内外循证医学证据,结合临床实践经验,对化疗相关腹泻的定义、发病机制、分类、评估、诊断、干预和预防进行充分的评估与讨论,最终形成《化疗相关腹泻全程管理中国专家共识(2025年版)》,以便进一步规范对化疗相关腹泻的全程管理。本共识已在国际实践指南注册与透明化平台(Practice guideline REgistration for transPAREncy,PREPARE)上注册,注册编号为PREPARE-2024CN1246。
