The plasma membrane(PM)plays an essential role in maintaining cell homeostasis,therefore,timely and effective repair of damage caused by factors such as mechanical rupture,pore-forming toxins,or pore-forming proteins ...The plasma membrane(PM)plays an essential role in maintaining cell homeostasis,therefore,timely and effective repair of damage caused by factors such as mechanical rupture,pore-forming toxins,or pore-forming proteins is crucial for cell survival.PM damage induces membrane rupture and stimulates an immune response.However,damage resulting from regulated cell death processes,including pyroptosis,ferroptosis,and necroptosis,cannot be repaired by simple sealing mechanisms and thus,requires specialized repair machinery.Recent research has identified a PM repair mechanism of regulated cell death-related injury,mediated by the endosomal sorting complexes required for transport(ESCRT)machinery.Here,we review recent progress in elucidating the ESCRT machinery-mediated repair mechanism of PM injury,with particular focus on processes related to regulated cell death.This overview,along with continued research in this field,may provide novel insights into therapeutic targets for diseases associated with dysregulation of regulated cell death pathways.展开更多
This article provides a short review on the importance of the detailed analysis of a Langmuir probe I-V trace in a multi-Maxwellian plasma,and discuss proper procedures analyzing Langmuir probe I-V traces in bi-Maxwel...This article provides a short review on the importance of the detailed analysis of a Langmuir probe I-V trace in a multi-Maxwellian plasma,and discuss proper procedures analyzing Langmuir probe I-V traces in bi-Maxwellian and triple-Maxwellian Electron Energy Distribution Function(EEDF)plasmas.Discus⁃sion and demonstration of procedures include the treatment of the ion saturation current,electron saturation cur⁃rent,space-charge effects on the I-V trace,and most importantly how to properly isolate and fit for each electron group present in an I-V trace reflecting a mult-Maxwellian EEDF,as well as how having a multi-Maxwellian EEDF affects the procedures of treating the ion and electron saturation currents.Shortcomings of common improp⁃er procedures are discussed and demonstrated with simulated I-V traces to show how these procedures gives false measurements.展开更多
在30kW级直流电弧等离子体喷射化学气相沉积(DC Arc P lasm a Jet CVD)设备上,采用Ar-H2-CH4混合气体,通过调节甲烷浓度以及控制其他沉积参数,在Mo衬底上沉积出微/纳米复合自支撑金刚石膜。实验表明,当微米金刚石膜层沉积结束后,在随后...在30kW级直流电弧等离子体喷射化学气相沉积(DC Arc P lasm a Jet CVD)设备上,采用Ar-H2-CH4混合气体,通过调节甲烷浓度以及控制其他沉积参数,在Mo衬底上沉积出微/纳米复合自支撑金刚石膜。实验表明,当微米金刚石膜层沉积结束后,在随后的沉积中,随着甲烷浓度的增加,金刚石膜表面的晶粒大小是逐渐减小的。当甲烷浓度达到20%以上时,金刚石膜生长面晶粒呈现菜花状的小晶团,膜体侧面已经没有了粗大的柱状晶,而是呈现出光滑的断口,对该层进行拉曼谱分析显示,位于1145 cm-1附近有一定强度的散射峰出现。这说明所沉积的晶粒全部变为纳米级尺寸。展开更多
We investigate computationally the attenuation and reflection of Terahertz （THz） wave using targets coated with plasmas. The simulators are the Wentzel-Kramer-Brillouin （WKB） method and finite-difference timedoma...We investigate computationally the attenuation and reflection of Terahertz （THz） wave using targets coated with plasmas. The simulators are the Wentzel-Kramer-Brillouin （WKB） method and finite-difference timedomain （FDTD） method. The relation between the frequency of the incident electromagnetic （EM） wave and the attenuation caused by unmagnitized plasma is analyzed. The results demonstrate that the amount of absorbed power is a decreasing function of the EM wave frequency and the plasma collision frequency. For THz band incident wave, the attenuation that is caused by plasma is small when the plasma has common density and the collision frequency. This conclusion has fine applying foreground for plasma anti stealth.展开更多
Laser Induced Breakdown Spectroscopic(LIBS)technique was used to detect calcium and silicon in an unknown sample.In this method plasma was generated by Nd∶YAG laser of wavelength 1 064 nm with energy 400 mJ and pulse...Laser Induced Breakdown Spectroscopic(LIBS)technique was used to detect calcium and silicon in an unknown sample.In this method plasma was generated by Nd∶YAG laser of wavelength 1 064 nm with energy 400 mJ and pulse duration between 5~10ns.The method was applied for the qualitative as well as quantitative analysis.In the qualitative analysis,the electron number density(Ne)of plasma containing calcium and silicon is determined showing that Neof neutral particles is equivalent to 1016(cm-3)whereas for ionized particles it is 1017(cm-3).Plasma temperature is measured using Boltzmann plot method which must be greater than 10 000 k.Intensity ratio method is used for the quantitative analysis shows various elements in abundance with calcium and silicon in majority.展开更多
Failure data from oilfield showed that casings which were designed according to API standards were deformed and collapsed in salt formations. The main reason for decrease in strength may be caused by non-uniform loadi...Failure data from oilfield showed that casings which were designed according to API standards were deformed and collapsed in salt formations. The main reason for decrease in strength may be caused by non-uniform loading(NUL) that was not considered in traditional casing collapsing strength design or that the designing method should be improved and developed. Obviously, the calculation of casing collapse strength is one of the key factors in casing design. However, the effect of NUL on casing collapse strength was generally neglected in the present computational methods. Therefore, a mechanical model which can calculate casing collapse strength under NUL was established based on the curved beam theory of the elasticity and was solved using displacement method. Simultaneously, three anti-collapse experiments were performed on C110 casing under NUL, and the strain and deformation laws of three casings in the process of collapse were obtained by the electrical method. Yield limit of every casing was obtained by analyzing those data. Experimental results are consistent with the results of calculation of new model. It indicates that the model can be used to calculate yield limit loading of casings under NUL.展开更多
The piecewise linear recursive convolution （PLRC） finite-different time-domain （FDTD） method greatly improves accuracy over the original recursive convolution （RC） FDTD approach but retains its speed and efficie...The piecewise linear recursive convolution （PLRC） finite-different time-domain （FDTD） method greatly improves accuracy over the original recursive convolution （RC） FDTD approach but retains its speed and efficiency advantages. A PLRC-FDTD formulation for magnetized plasma which incorporates both anisotropy and frequency dispersion at the same time is presented, enabled the transient analysis of magnetized plasma media. The technique is illustrated by numerical simulations the reflection and transmission coefficients through a magnetized plasma layer. The results show that the PLRC-FDTD method has significantly improved the accuracy over the original RC method.展开更多
In national economy and national defense, a lot of ma chine components become worthless early because of wear and tear and corrode. It leads to huge loss of resource and material. Surface hardening of the steel cou ld...In national economy and national defense, a lot of ma chine components become worthless early because of wear and tear and corrode. It leads to huge loss of resource and material. Surface hardening of the steel cou ld form a hard, wearable, corrode-resisting layer on the surface to enhance the mechanical property of the machine component. From 1980s, there is a new method of surface hardening that is heating with plasma arc. It overcomes the shortage of old methods and is adopted in automotive product industry. The plasma equipm ent is small and easy to be controlled, so it could be installed on a robot and moved everywhere. This paper analyzed the character of the plasma at first, then studied the plasm a arc as Guess distribution circular heat source to create the surface hardening temperature field and heating process. The method of the plasma arc surface har dening technology is given. This paper describes hardware design of the plasma arc surface-hardening robot and analyzes its kinematics. This robot is a humanoid form robot with a mobile p latform, a 7 DOF redundancy arm and a 2 DOF trunk. The footprint is an important feature for the robot that has to move in a cluttered environment. Thus the mob ile platform of the plasma arc robot is an omni-directional mobile robot with o rthogonal-wheel assemblies. The trunk is important for keep balance of the robo t. Thus a series spring is fixed in the trunk to provide accurate force feedback at each direction and insulate the shock loads from arm and mobile platform. Th e redundancy arm configuration is similar to a broadly simplified model of the h uman arm with 7 DOF. The maximum radius is about 1 m with a maximum load of abou t 1 kg. The redundancy of the 7 DOF allows the handling of situation in whic h additional movement constraints have to meet and avoids static or dynamic obst acles. It has better adaptation to typical human environment and to allow for hu man-like behavioral strategies in solving complex tasks. This robot will be applied widely in shipbuilding industry, mining industry and automotive product industry.展开更多
A sputtering-type microwave multipolar ECR plasma processing for preparing thin films, is built with Nd-Fe-B magnets and 2.45 GHz, TE<sub>10</sub> mode microwave. The plasma distributions in the axial dire...A sputtering-type microwave multipolar ECR plasma processing for preparing thin films, is built with Nd-Fe-B magnets and 2.45 GHz, TE<sub>10</sub> mode microwave. The plasma distributions in the axial direction, which is important for preparing thin films, are found to be very sensitive to the magnetic potential fields in plasma chamber. The plasma parameters are also influenced by the background gas pressure.展开更多
Ti-6 Al-4 V-Si3 N4 composites were effectively fabricated by spark plasma sintering(SPS) technique. The addition of Si_3 N_4 on Ti-6 AI-4 V was varied from 5% to 15%(wt fraction). The effect of Si_3 N_4 addition on th...Ti-6 Al-4 V-Si3 N4 composites were effectively fabricated by spark plasma sintering(SPS) technique. The addition of Si_3 N_4 on Ti-6 AI-4 V was varied from 5% to 15%(wt fraction). The effect of Si_3 N_4 addition on the densification, microstructure, and microhardness and corrosion behaviour of Ti-6 Al-4 V was investigated.An increase in microhardness value was recorded from 325.46 HV_(0.1) to 585.73 HV_(0.1). X-ray diffraction(XRD) analysis showed that the intensity of diffraction peaks of Si3 N4 phase in the composites increased.The sintered Ti-6 Al-4 V reinforced with Si_3 N_4 compacts revealed the non-existence of intermediate phases, such as TiSi_2(titanium silicide) which was expected. SEM analysis of the spark plasma sintered composites revealed a and β phase microstructures in Ti-6 Al-4 V with uniform distribution of Si3 N4 particulates in the matrix. The corrosion resistance property of the material was improved by the addition of Si_3 N_4 from 0.986629 mm/year to 0.030547 mm/year.展开更多
Nanostructured FeS-SiC coating was deposited by atmospheric plasma spraying（APS）.The microstructure and phase composition of the coating were characterized with SEM and XRD,respectively.In addition,the size distribu...Nanostructured FeS-SiC coating was deposited by atmospheric plasma spraying（APS）.The microstructure and phase composition of the coating were characterized with SEM and XRD,respectively.In addition,the size distribution of the reconstituted powders and the porosity of the coating have been measured.It was found that the reconstitiuted powers with sizes in the range of 20 to 80 μm had excellent flowability and were suitable for plasma spraying process.The as-sprayed FeS-SiC composite coating exhibited a bimodal distribution with small grains（30～80nm） and large grains（100～200nm）.The coating was mainly composed of FeS and SiC,a small quantity of Fe1-xS and oxide were also found.The porosity of the coating was approximately 19%.展开更多
文摘The plasma membrane(PM)plays an essential role in maintaining cell homeostasis,therefore,timely and effective repair of damage caused by factors such as mechanical rupture,pore-forming toxins,or pore-forming proteins is crucial for cell survival.PM damage induces membrane rupture and stimulates an immune response.However,damage resulting from regulated cell death processes,including pyroptosis,ferroptosis,and necroptosis,cannot be repaired by simple sealing mechanisms and thus,requires specialized repair machinery.Recent research has identified a PM repair mechanism of regulated cell death-related injury,mediated by the endosomal sorting complexes required for transport(ESCRT)machinery.Here,we review recent progress in elucidating the ESCRT machinery-mediated repair mechanism of PM injury,with particular focus on processes related to regulated cell death.This overview,along with continued research in this field,may provide novel insights into therapeutic targets for diseases associated with dysregulation of regulated cell death pathways.
文摘This article provides a short review on the importance of the detailed analysis of a Langmuir probe I-V trace in a multi-Maxwellian plasma,and discuss proper procedures analyzing Langmuir probe I-V traces in bi-Maxwellian and triple-Maxwellian Electron Energy Distribution Function(EEDF)plasmas.Discus⁃sion and demonstration of procedures include the treatment of the ion saturation current,electron saturation cur⁃rent,space-charge effects on the I-V trace,and most importantly how to properly isolate and fit for each electron group present in an I-V trace reflecting a mult-Maxwellian EEDF,as well as how having a multi-Maxwellian EEDF affects the procedures of treating the ion and electron saturation currents.Shortcomings of common improp⁃er procedures are discussed and demonstrated with simulated I-V traces to show how these procedures gives false measurements.
文摘在30kW级直流电弧等离子体喷射化学气相沉积(DC Arc P lasm a Jet CVD)设备上,采用Ar-H2-CH4混合气体,通过调节甲烷浓度以及控制其他沉积参数,在Mo衬底上沉积出微/纳米复合自支撑金刚石膜。实验表明,当微米金刚石膜层沉积结束后,在随后的沉积中,随着甲烷浓度的增加,金刚石膜表面的晶粒大小是逐渐减小的。当甲烷浓度达到20%以上时,金刚石膜生长面晶粒呈现菜花状的小晶团,膜体侧面已经没有了粗大的柱状晶,而是呈现出光滑的断口,对该层进行拉曼谱分析显示,位于1145 cm-1附近有一定强度的散射峰出现。这说明所沉积的晶粒全部变为纳米级尺寸。
基金the National Natural Science Foundation of China (60771017)the China Postdoctoral ScienceFoundation (20060390272)
文摘We investigate computationally the attenuation and reflection of Terahertz （THz） wave using targets coated with plasmas. The simulators are the Wentzel-Kramer-Brillouin （WKB） method and finite-difference timedomain （FDTD） method. The relation between the frequency of the incident electromagnetic （EM） wave and the attenuation caused by unmagnitized plasma is analyzed. The results demonstrate that the amount of absorbed power is a decreasing function of the EM wave frequency and the plasma collision frequency. For THz band incident wave, the attenuation that is caused by plasma is small when the plasma has common density and the collision frequency. This conclusion has fine applying foreground for plasma anti stealth.
文摘Laser Induced Breakdown Spectroscopic(LIBS)technique was used to detect calcium and silicon in an unknown sample.In this method plasma was generated by Nd∶YAG laser of wavelength 1 064 nm with energy 400 mJ and pulse duration between 5~10ns.The method was applied for the qualitative as well as quantitative analysis.In the qualitative analysis,the electron number density(Ne)of plasma containing calcium and silicon is determined showing that Neof neutral particles is equivalent to 1016(cm-3)whereas for ionized particles it is 1017(cm-3).Plasma temperature is measured using Boltzmann plot method which must be greater than 10 000 k.Intensity ratio method is used for the quantitative analysis shows various elements in abundance with calcium and silicon in majority.
基金Projects(51074135,51274170,51004084)supported by the National Natural Science Foundation of China
文摘Failure data from oilfield showed that casings which were designed according to API standards were deformed and collapsed in salt formations. The main reason for decrease in strength may be caused by non-uniform loading(NUL) that was not considered in traditional casing collapsing strength design or that the designing method should be improved and developed. Obviously, the calculation of casing collapse strength is one of the key factors in casing design. However, the effect of NUL on casing collapse strength was generally neglected in the present computational methods. Therefore, a mechanical model which can calculate casing collapse strength under NUL was established based on the curved beam theory of the elasticity and was solved using displacement method. Simultaneously, three anti-collapse experiments were performed on C110 casing under NUL, and the strain and deformation laws of three casings in the process of collapse were obtained by the electrical method. Yield limit of every casing was obtained by analyzing those data. Experimental results are consistent with the results of calculation of new model. It indicates that the model can be used to calculate yield limit loading of casings under NUL.
基金The project was supported by the National Natural Science Foundation of China (60471002) and the Jiangxi ProvincialNatural Science Foundation (0412014)
文摘The piecewise linear recursive convolution （PLRC） finite-different time-domain （FDTD） method greatly improves accuracy over the original recursive convolution （RC） FDTD approach but retains its speed and efficiency advantages. A PLRC-FDTD formulation for magnetized plasma which incorporates both anisotropy and frequency dispersion at the same time is presented, enabled the transient analysis of magnetized plasma media. The technique is illustrated by numerical simulations the reflection and transmission coefficients through a magnetized plasma layer. The results show that the PLRC-FDTD method has significantly improved the accuracy over the original RC method.
文摘In national economy and national defense, a lot of ma chine components become worthless early because of wear and tear and corrode. It leads to huge loss of resource and material. Surface hardening of the steel cou ld form a hard, wearable, corrode-resisting layer on the surface to enhance the mechanical property of the machine component. From 1980s, there is a new method of surface hardening that is heating with plasma arc. It overcomes the shortage of old methods and is adopted in automotive product industry. The plasma equipm ent is small and easy to be controlled, so it could be installed on a robot and moved everywhere. This paper analyzed the character of the plasma at first, then studied the plasm a arc as Guess distribution circular heat source to create the surface hardening temperature field and heating process. The method of the plasma arc surface har dening technology is given. This paper describes hardware design of the plasma arc surface-hardening robot and analyzes its kinematics. This robot is a humanoid form robot with a mobile p latform, a 7 DOF redundancy arm and a 2 DOF trunk. The footprint is an important feature for the robot that has to move in a cluttered environment. Thus the mob ile platform of the plasma arc robot is an omni-directional mobile robot with o rthogonal-wheel assemblies. The trunk is important for keep balance of the robo t. Thus a series spring is fixed in the trunk to provide accurate force feedback at each direction and insulate the shock loads from arm and mobile platform. Th e redundancy arm configuration is similar to a broadly simplified model of the h uman arm with 7 DOF. The maximum radius is about 1 m with a maximum load of abou t 1 kg. The redundancy of the 7 DOF allows the handling of situation in whic h additional movement constraints have to meet and avoids static or dynamic obst acles. It has better adaptation to typical human environment and to allow for hu man-like behavioral strategies in solving complex tasks. This robot will be applied widely in shipbuilding industry, mining industry and automotive product industry.
文摘A sputtering-type microwave multipolar ECR plasma processing for preparing thin films, is built with Nd-Fe-B magnets and 2.45 GHz, TE<sub>10</sub> mode microwave. The plasma distributions in the axial direction, which is important for preparing thin films, are found to be very sensitive to the magnetic potential fields in plasma chamber. The plasma parameters are also influenced by the background gas pressure.
基金financial support from National Research Foundation(NRF), Pretoria, South Africa
文摘Ti-6 Al-4 V-Si3 N4 composites were effectively fabricated by spark plasma sintering(SPS) technique. The addition of Si_3 N_4 on Ti-6 AI-4 V was varied from 5% to 15%(wt fraction). The effect of Si_3 N_4 addition on the densification, microstructure, and microhardness and corrosion behaviour of Ti-6 Al-4 V was investigated.An increase in microhardness value was recorded from 325.46 HV_(0.1) to 585.73 HV_(0.1). X-ray diffraction(XRD) analysis showed that the intensity of diffraction peaks of Si3 N4 phase in the composites increased.The sintered Ti-6 Al-4 V reinforced with Si_3 N_4 compacts revealed the non-existence of intermediate phases, such as TiSi_2(titanium silicide) which was expected. SEM analysis of the spark plasma sintered composites revealed a and β phase microstructures in Ti-6 Al-4 V with uniform distribution of Si3 N4 particulates in the matrix. The corrosion resistance property of the material was improved by the addition of Si_3 N_4 from 0.986629 mm/year to 0.030547 mm/year.
基金The authors would like to thank National Natural Science Foundation of China (No. 50375015) for supporting.
文摘Nanostructured FeS-SiC coating was deposited by atmospheric plasma spraying（APS）.The microstructure and phase composition of the coating were characterized with SEM and XRD,respectively.In addition,the size distribution of the reconstituted powders and the porosity of the coating have been measured.It was found that the reconstitiuted powers with sizes in the range of 20 to 80 μm had excellent flowability and were suitable for plasma spraying process.The as-sprayed FeS-SiC composite coating exhibited a bimodal distribution with small grains（30～80nm） and large grains（100～200nm）.The coating was mainly composed of FeS and SiC,a small quantity of Fe1-xS and oxide were also found.The porosity of the coating was approximately 19%.
