摘要
4-氨基磺酰基苯磺酰氯是一种重要的医药化工中间体。本文以4-氨基苯磺酰胺为原料,进一步反应得到目标化合物。该合成方法操作简便、后处理操作简便,花费时间少且产物纯度高,产品收率为40.21%;此方法为4-氨基磺酰基苯磺酰氯的合成提供了合成路线,也为进一步相关类似的合成研究奠定基础。
4-Aminosulfonylbenzenesulfonyl chloride is an important pharmaceutical and chemical intermediate. In this paper, the target compound was obtained by one step reaction using 4-aminoben- zenesulfonamide as raw material. The synthesis method is simple, the post-processing operation is simple, the time is less, the product purity is high, and the product yield is 50.21%;this method provides a synthetic route for the synthesis of 4-aminosulfonylbenzenesulfonyl chloride, and also lays a foundation for further similar synthesis research.
出处
《药物化学》
2024年第2期96-100,共5页
Hans Journal of Medicinal Chemistry
