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慢性创面细菌生物膜治疗策略研究进展

Research Progress on Therapeutic Strategies of Bacterial Biofilm in Chronic Wounds
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摘要 慢性创面的难治愈性与细菌生物膜(BBF)的形成相关,治疗需消耗大量医疗资源,因此BBF成为临床医生与研究者所关注的重点问题。本文主要从BBF概述、诊断、预防与治疗三方面进行综述,重点关注其治疗策略的选择,包括清创、负压疗法、抗生物膜剂和各种创新敷料的应用,目前临床中BBF多以联合治疗为主,希望本文能为临床慢性创面BBF治疗提供新的思路与建议。 The curability of chronic wounds is related to the formation of bacterial biofilm (BBF), and the treatment needs to consume a lot of medical resources. Therefore, BBF has become the focus of at-tention of clinicians and researchers. This paper mainly reviews the overview, diagnosis, prevention and treatment of BBF, focusing on the selection of therapeutic strategies, including debridement, negative pressure therapy, anti-biological film agent and the application of various innovative dressings. Currently, combination therapy is mainly used for BBF in clinical practice, hoping that this paper can provide new ideas and suggestions for the treatment of BBF in clinical chronic wounds.
作者 杜宗玥 曾勇
出处 《临床医学进展》 2023年第6期9680-9689,共10页 Advances in Clinical Medicine
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  • 1刘小平,卢金利,吴素歌,杨芳,李明众.芦荟凝胶对大鼠Ⅱ度放射性皮炎创面愈合及表皮生长因子、碱性成纤维细胞生长因子表达的影响[J].西安交通大学学报(医学版),2006,27(1):66-68. 被引量:31
  • 2Wolcott RD,Kennedy JP,Dowd SE. Regular debridement is the main tool for maintaining a healthy wound bed in most chronic[J].J Wound Care,2009,18(2):54-56.
  • 3Kim PJ,Steinberg JS. Wound care:biofilm and its impact on the latest treatment modalities for ulcerations of the diabetic foot[J]. Semin Vasc Surg,2012,25(2):70-74.
  • 4Caputo WJ,Beggs DJ,DeFede JL,et al. A prospective rando- raised controlled clinical trial comparing hydrosurgcry de- bridement with conventional surgical debridement in lower ex- tremity ulcers[J]. Int Wound J,2008,5(2):288-294.
  • 5Bradley BH,Cunningham M. Biofihns in chronic wounds and the potential role of negative pressure wound therapy [J].J Wound Ostomy Continence Nurs,2013,40(2):143-149.
  • 6Gabriel A,Shores J,Heinrich C,et al. Negative pressure wound therapy with instillation:a pilot study describing a new method for treating infected wounds[J]. Int Wound J,2008,5(3): 399-413.
  • 7Davis K,ttills J,Barker J,et al. Simultaneous irrigation and negative pressure wound therapy enhances wound healing and reduces wound bioburden in a porcine model[J]. Wound Re- pair Regen,2013,2l (6) :869-875.
  • 8Ngo QD,Vickery K,Deva AK. The effect of topical negative pressure on wound bio?lms using an in vitro wound model [J]. Wound Repair Regen,2012,20(1):83-90.
  • 9Erlangga Y,Xavier J,Martin C,et al. High bacterial load in negative pressure wound therapy(NPWT) foams used in the treatment of chronic wounds[J].Wound Repair and Regene, 2013,21(5) :677-681.
  • 10Erriu M,Blus C,Szmukler-Moncler S,et al.Microbial biofihnmodulation by ultrasound:cmTent concepts and controversies [ J 1. Uhrason Sonochem, 20l 4,21 ( 1 ) : 15-22.

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