摘要
目的 探讨小儿原发性睾丸肿瘤的诊治。方法 分析小儿原发性睾丸肿瘤 32例 ,其中卵黄囊瘤 1 6例 ,畸胎瘤 1 0例 ,胚胎型横纹肌肉瘤 4例 ,表皮样囊肿 2例。所有病例均行手术治疗 ,术中行冰冻切片活检 ,良性者行保留睾丸手术 ;恶性者行根治性睾丸切除、腹股沟淋巴结清扫术。2 0例恶性肿瘤病人术后行系统化疗。结果 术中冰冻病理与术后病理结果完全一致。 2 4例获得随访 ,除 4例卵黄囊瘤病人术后 1年内因广泛转移死亡外 ,其余病例均无瘤生存 4个月至 7年 ,平均 73个月。结论 超声对小儿原发性睾丸肿瘤有诊断价值 ,列为常规检查。手术为首选的治疗 ,术中冰冻切片活检非常必要。睾丸良性肿瘤患儿行保留睾丸手术对其生理功能、美观及心理方面均有重要意义。对预后好的病例尽量减少化疗 。
Objeotiver To discuss the diagnosis and treatment of primary testicular tumors in children. Methods Thirty twe patients who underwent treatment of primary testicular tumors in children between 5 months and 12 years from 1993 to 2003 were retrospectively reviewed. Frozen section pathological examination during in operation was done in all the patients. Depending on it, testicle sparing surgery or radical orchidectomy was performed accordingly. Twenty patients with malignant testicular tumors under went chemotherapy after surgery. Results There was no contradiction between the findings of paraftin section pathological examination and frozen section. The average follow up period in 24 patients was 73 months (ranged from 5 months to 7 years). Four patients with yolk sac tumor died of distant metastasis of the tumor in 1 year after surgery. Others were alive without tumor for 4 months to 7 years. Conclusious Ultrasonography was valuable for the diagnosis of the primary testicular tumor. Surgery should be the treatment of first choice. It was important to send for frozen section pathology during operation. According to frozen section findings, it could be decided whether the testis could be spared, which is of importance in regard to aesthetics, psychology and function for children with benign testicular tumors. Postoperative chemotherapy was beneficial in raising surrival rate in children with malignant tumors in whom the prognosis was poor
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2004年第6期547-548,共2页
Medical Journal of Chinese People's Liberation Army
关键词
睾丸肿瘤
儿童
手术
冰冻活检
化疗
testicular tumor
children
surgery
frozen section
chemotherapy
